Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10120369 | 0.93 | GABRA1 (0.51) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| SCHEMBL5253722 | 0.86 | KDM4E (0.52) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL10614798 | 0.85 | GABRA1 (0.56) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| SCHEMBL10527021 | 0.79 | TSPO (0.48) | KDM4EALBOPRK1KCNH2RAB9A | |
| SCHEMBL10120392 | 0.79 | GABRA1 (0.39) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| SCHEMBL6011806 | 0.78 | KDM4E (0.52) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| SCHEMBL6216568 | 0.78 | KDM4E (0.52) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| SCHEMBL4723542 | 0.78 | TP53 (0.51) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| SCHEMBL7998726 | 0.77 | TP53 (0.56) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| SCHEMBL6216380 | 0.76 | KDM4E (0.50) | GABRA1GABRB2KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539751-B1 | PROCESS FOR THE PREPARATION OF IMIDAZO(1,2-A)PYRIDINE-3-ACETAMIDES | SCINOPHARM TAIWAN LTD (TW) | 2008-05-07 | — | — | EP | claimed |
| US-6861525-B2 | Process for the preparation imidazo[1,2-A]pyridine-3-acetamides | SCINOPHARM TAIWAN, LTD. (TW) | 2005-03-01 | — | — | US | claimed |
| US-20040010146-A1 | Process for the preparation imidazo[1,2-A]pyridine-3-acetamides | SCINOPHARM TAIWAN, LTD. | 2004-01-15 | — | — | US | claimed |
| CN-114249723-B | Preparation method of zolpidem and key intermediate thereof | 鲁南制药集团股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-114249723-A | Preparation method of zolpidem and key intermediate thereof | 鲁南制药集团股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| US-8101633-B2 | Preparation and utility of substituted imidazopyridine compounds with hypnotic effects | AUSPEX PHARMACEUTICALS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-7772248-B2 | Preparation and utility of substituted imidazopyridine compounds with hypnotic effects | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-20100121067-A1 | PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| US-20100105720-A1 | PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-04-29 | — | — | US | disclosed |
| EP-1809627-B1 | SYNTHESIS OF HETEROARYL ACETAMIDES FROM REACTION MIXTURES HAVING REDUCED WATER CONTENT | MALLINCKRODT INC (US) | 2009-12-09 | — | — | EP | disclosed |
| US-7498439-B2 | Synthesis of heteroaryl acetamides from reaction mixtures having reduced water content | MALLINCKRODT INC. (US) | 2009-03-03 | — | — | US | disclosed |
| EP-1575952-B1 | SYNTHESIS OF HETEROARYL ACETAMIDES | MALLINCKRODT INC (US) | 2009-02-18 | — | — | EP | disclosed |
| US-7385056-B2 | Synthesis of heteroaryl acetamides | MALLINCKRODT INC. (US) | 2008-06-10 | — | — | US | disclosed |
| US-7385056-B2 | Synthesis of heteroaryl acetamides | MALLINCKRODT INC. (US) | 2008-06-10 | — | — | US | disclosed |
| EP-1539751-B1 | PROCESS FOR THE PREPARATION OF IMIDAZO(1,2-A)PYRIDINE-3-ACETAMIDES | SCINOPHARM TAIWAN LTD (TW) | 2008-05-07 | — | — | EP | disclosed |
| US-20070281965-A1 | PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS | AUSPEX PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | US | disclosed |
| US-20070213537-A1 | Synthesis Of Heteroaryl Acetamides From Reaction Mixtures Having Reduced Water Content | MALLINCKRODT INC. | 2007-09-13 | — | — | US | disclosed |
| US-6861525-B2 | Process for the preparation imidazo[1,2-A]pyridine-3-acetamides | SCINOPHARM TAIWAN, LTD. (TW) | 2005-03-01 | — | — | US | disclosed |
| US-20040010146-A1 | Process for the preparation imidazo[1,2-A]pyridine-3-acetamides | SCINOPHARM TAIWAN, LTD. | 2004-01-15 | — | — | US | disclosed |
| US-4794185-A | TREATING CORRESPONDING CHLORO COMPOUND WITH REDUCING AGENT | SYNTHELABO (FR) | 1988-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121067-A1 | PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS | GABRA4, GABRP, GABBR1 | GABRA1 6/4885GABRB2 17/4885KDM4E 695/4885 |
| US-20070281965-A1 | PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS | GABRA4, GABRP, GABBR1 | GABRA1 6/4885GABRB2 17/4885KDM4E 695/4885 |
| US-20100105720-A1 | PREPARATION AND UTILITY OF SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS WITH HYPNOTIC EFFECTS | GABRA4, GABRP, GABBR1 | GABRA1 6/4885GABRB2 17/4885KDM4E 695/4885 |
| US-20070213537-A1 | Synthesis Of Heteroaryl Acetamides From Reaction Mixtures Having Reduced Water Content | SQSTM1, CYP3A43, HTR2A | GABRA1 229/4885GABRB2 869/4885KDM4E 2530/4885 |
| US-20040010146-A1 | Process for the preparation imidazo[1,2-A]pyridine-3-acetamides | AAK1, ACP3, AP2M1 | GABRA1 332/4885GABRB2 1128/4885KDM4E 695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.