Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29065806 | 1.00 | ALDH1A1 (0.49) | ALDH1A1RAB9AALOX5NPC1HPGD | |
| SCHEMBL28814771 | 1.00 | ALDH1A1 (0.49) | ALDH1A1RAB9AALOX5NPC1HPGD | |
| SCHEMBL27987923 | 0.86 | RAB9A (0.50) | ALDH1A1RAB9AALOX5NPC1HPGD | |
| SCHEMBL4368395 | 0.84 | HPGD (0.46) | ALDH1A1RAB9AALOX5NPC1HPGD | |
| SCHEMBL5516780 | 0.84 | ALOX5 (0.45) | ALDH1A1RAB9AALOX5NPC1HPGD | |
| SCHEMBL5474569 | 0.83 | ALOX5 (0.56) | ALDH1A1RAB9AALOX5NPC1HPGD | |
| SCHEMBL27347277 | 0.83 | ALOX5 (0.47) | ALDH1A1RAB9AALOX5NPC1HPGD | |
| SCHEMBL658090 | 0.82 | CES2 (0.46) | ALDH1A1RAB9AALOX5NPC1HPGD | |
| SCHEMBL5179686 | 0.82 | ALOX5 (0.44) | ALDH1A1RAB9AALOX5NPC1HPGD | |
| SCHEMBL5166330 | 0.81 | CYP2C19 (0.49) | ALDH1A1RAB9AALOX5NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891838-B | Synthesis method of dorzolamide hydrochloride intermediate (S) -3- (2-thiophenyl) -butyric acid | 株洲壹诺生物技术有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-114891838-B | Synthesis method of dorzolamide hydrochloride intermediate (S) -3- (2-thiophenyl) -butyric acid | 株洲壹诺生物技术有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-114891838-B | Synthesis method of dorzolamide hydrochloride intermediate (S) -3- (2-thiophenyl) -butyric acid | 株洲壹诺生物技术有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-114891838-B | Synthesis method of dorzolamide hydrochloride intermediate (S) -3- (2-thiophenyl) -butyric acid | 株洲壹诺生物技术有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-114891838-A | Synthesis method of dorzolamide hydrochloride intermediate (S) -3- (2-thiophenylthio) -butyric acid | 株洲壹诺生物技术有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114891838-A | Synthesis method of dorzolamide hydrochloride intermediate (S) -3- (2-thiophenylthio) -butyric acid | 株洲壹诺生物技术有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-102566269-B | Coloured composition, colour filter and display element | JSR株式会社 | 2016-06-15 | — | — | CN | disclosed |
| EP-2755645-A1 | PHARMACEUTICAL COMBINATIONS INCLUDING ANTI-INFLAMMATORY AND ANTIOXIDANT CONJUGATES USEFUL FOR TREATING METABOLIC DISORDERS | Genmedica Therapeutics SL (ES) | 2014-07-23 | — | — | EP | disclosed |
| US-8765984-B2 | Methods and systems for making thiol compounds from terminal olefinic compounds | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2014-07-01 | — | — | US | disclosed |
| WO-2013037985-A1 | PHARMACEUTICAL COMBINATIONS INCLUDING ANTI-INFLAMMATORY AND ANTIOXIDANT CONJUGATES USEFUL FOR TREATING METABOLIC DISORDERS | GENMEDICA THERAPUTICS SL (ES) | 2013-03-21 | — | — | WO | disclosed |
| US-20080103139-A1 | 3-Carbamoyl-2-Pyridone Derivative | SHIONOGI & CO. LTD. (JP) | 2008-05-01 | — | — | US | disclosed |
| US-6825358-B2 | AS ORGANIC SEMICONDUCTORS CAN BE DISSOLVED IN COMMON ORGANIC SOLVENTS AND APPLIED TO THE SURFACE OF A SUBSTRATE USING INEXPENSIVE, LOW-TEMPERATURE SOLUTION-BASED PROCESSING SUCH AS SPIN-COATING, DIP-COATING, DROP-CASTING, ETC. | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2004-11-30 | — | — | US | disclosed |
| US-6414164-B1 | LOW COST, LOW TEMPERATURE ALTERNATIVES TO AMORPHOUS SILICON AS SEMICONDUCTING COMPONENT IN THIN FILM TRANSISTOR DEVICES | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2002-07-02 | — | — | US | disclosed |
| US-20020072618-A1 | Synthesis of soluble derivatives of sexithiophene and their use as the semiconducting channels in thin-film field-effect transistors | GLOBALFOUNDRIES U.S. INC. | 2002-06-13 | — | — | US | disclosed |
| CN-1053904-C | Novel N-pyridyl carboxamides and derivatives, processes for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 2000-06-28 | — | — | CN | disclosed |
| US-5843947-A | N-pyridyl carboxamides and derivatives | ADIR ET COMPAGNIE (FR) | 1998-12-01 | — | — | US | disclosed |
| US-5712294-A | N-pyridyl carboxamides and derivatives | ADIR ET COMPAGNIE (FR) | 1998-01-27 | — | — | US | disclosed |
| CN-1121074-A | Novel N-pyridyl carboxamides and derivatives, processes for their preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1996-04-24 | — | — | CN | disclosed |
| US-5177096-A | Angiotensin II receptor antagonist | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| US-4352753-A | 3-[[(2,3-Dihydro-1H-indol-2-yl)carbonyl]thio]propanoic (and acetic) acids as intermediates | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020072618-A1 | Synthesis of soluble derivatives of sexithiophene and their use as the semiconducting channels in thin-film field-effect transistors | SLC43A1, GFPT1, PHOSPHO1 | ALDH1A1 3675/4885RAB9A 3027/4885ALOX5 2508/4885 |
| US-20080103139-A1 | 3-Carbamoyl-2-Pyridone Derivative | CNR1, CNR2, HRH4 | ALDH1A1 4132/4885RAB9A 2496/4885ALOX5 829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.