Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16621492 | 0.83 | HAVCR2 (0.47) | KDM4EALDH1A1HSD17B10KMT2AGABRP | |
| SCHEMBL30819200 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL12786944 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL438198 | 0.81 | MAPK1 (0.63) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7498304 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL440411 | 0.81 | HAVCR2 (0.52) | ALDH1A1HSD17B10KMT2AMEN1HAVCR2 | |
| SCHEMBL442132 | 0.81 | TSHR (0.50) | KDM4EALDH1A1HSD17B10KMT2AMEN1 | |
| SCHEMBL440033 | 0.81 | KEAP1 (0.49) | ALDH1A1KMT2AMEN1HAVCR2ACHE | |
| SCHEMBL436681 | 0.81 | LMNA (0.63) | KDM4EALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL440698 | 0.81 | TP53 (0.50) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |