SCHEMBL436647

SCHEMBL436647

C1=C2CNCCCN2CCC1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 9/20 0.33
CHRNA4 P43681 9/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 1/20 0.32
CHRNA1 P02708 1/20 0.31
CHRNA7 P36544 1/20 0.31
CXCR4 P61073 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3810433 0.92 HTR2C (0.40) CHRNB2CHRNA4HTR2CHTR2B
SCHEMBL483180 0.81
Hydrochloric Acid SCHEMBL29689430 0.79
SCHEMBL1000578 0.78
SCHEMBL30169372 0.73 CHRNB2 (0.36) CHRNB2CHRNA4HTR2CHTR2BCHRNA1
SCHEMBL860227 0.73 HRH1 (0.41) CHRNB2CHRNA4HTR2CHTR2BCHRNA1
SCHEMBL30169373 0.73 CHRNB2 (0.36) CHRNB2CHRNA4HTR2CHTR2BCHRNA1
SCHEMBL15310285 0.73 TDP1 (0.36) CHRNB2CHRNA4HTR2CHTR2BCHRNA1
SCHEMBL15526123 0.73 USP2 (0.40) CHRNB2CHRNA4HTR2CHTR2BCHRNA1
SCHEMBL1300630 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663675-A1 BI-COMPONENT, SOLVENT-FREE POLYURETHANE COMPOSITION FOR PRODUCING IMITATION LEATHERS, BY SPRAY APPLICATION C.O.I.M. S.p.A.- Chimica Organica Industriale Milanese (IT) 2025-12-17 EP claimed
EP-4662215-A1 PROCESS FOR PREPARING TRILACICLIB OR A SALT THEREOF OLON S.p.A. (IT) 2025-12-17 EP claimed
WO-2024165950-A1 PROCESS FOR PREPARING TRILACICLIB OR A SALT THEREOF OLON S.P.A. (IT) 2024-08-15 WO claimed
US-11476422-B2 Anthradithiophene derivatives, process for the preparation thereof and polymers that contain them ENI S.P.A. (IT) 2022-10-18 US claimed
US-20210005817-A1 ANTHRADITHIOPHENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND POLYMERS THAT CONTAIN THEM ENI S.P.A. (IT) 2021-01-07 US claimed
EP-2563833-B1 PROCESS FOR PRODUCING RIGID POLYURETHANE FOAMS BASF SE (DE) 2015-02-25 EP claimed
EP-2542612-B1 PROCESS FOR PREPARING POLYETHER ALCOHOLS BASF SE (DE) 2014-04-30 EP claimed
US-20110263742-A1 PROCESS FOR PREPARING POLYETHER ALCOHOLS BASF SE (DE) 2011-10-27 US claimed
US-20110263737-A1 PROCESS FOR PRODUCING RIGID POLYURETHANE FOAMS BASF SE (DE) 2011-10-27 US claimed
US-20110218324-A1 PREPARING POLYETHER ALCOHOLS BASF SE (DE) 2011-09-08 US claimed
US-20100285311-A1 Dual component (aqueous) hybrid reactive resin system, method for production and use thereof CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2010-11-11 US claimed
US-20090198000-A1 Liquid fluorine-containing and two-component compositions for the surface treatment of mineral and non-mineral substrates EVONIK DEGUSSA GMBH (DE) 2009-08-06 US claimed
EP-2085442-A1 Compounds containing fluoride with improved surface characteristics Evonik Degussa GmbH (DE) 2009-08-05 EP claimed
WO-2007041571-A1 IMPROVED METHOD OF MAKING AMPHETAMINE FREE BASE CAMBREX CHARLES CITY, INC. (US) 2007-04-12 WO claimed
EP-1651704-A1 COATING COMPOSITIONS CONTAINING AMINOFUNCTIONAL SILICONE RESINS Dow Corning Corporation (US) 2006-05-03 EP claimed
EP-1144470-B1 THERMALLY STABLE POLYETHERAMINES DOW GLOBAL TECHNOLOGIES INC (US) 2005-11-30 EP claimed
WO-2005010078-A1 COATING COMPOSITIONS CONTAINING AMINOFUNCTIONAL SILICONE RESINS DOW CORNING CORPORATION (US) 2005-02-03 WO claimed
US-6589621-B1 A blend of an inorganic base, an organic base, a monofunctional organic nucleophile or a multifunctional organic nucleophile and a thermoplastic hydroxy-functionalized polyetheramine DOW GLOBAL TECHNOLOGIES INC. 2003-07-08 US claimed
EP-0247692-B1 ELASTOMERIC FLUID COMPOSITIONS, CROSSLINKING IN THE PRESENCE OF AMBIENT HUMIDITY, SUITABLE FOR USE IN SEALANTS ENICHEM SYNTHESIS S.p.A. (IT) 1990-07-18 EP claimed
EP-0190568-A1 Process for the preparation of spiroorthocarbonates BAYER AG (DE) 1986-08-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11476422-B2 Anthradithiophene derivatives, process for the preparation thereof and polymers that contain them OGFOD1, ALAD, OCIAD1 CHRNB2 4380/4885CHRNA4 3237/4885HTR2C 4218/4885
US-20210005817-A1 ANTHRADITHIOPHENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND POLYMERS THAT CONTAIN THEM OGFOD1, ALAD, OCIAD1 CHRNB2 4380/4885CHRNA4 3237/4885HTR2C 4218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.