Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.73 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.68 |
| ▸ | MAOB | P27338 | 8/20 | 0.68 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4369779 | 0.98 | LOXL2 (0.70) | LOXL2ST14MAOBSOS1TAAR1 | |
| SCHEMBL4209153 | 0.88 | ST14 (0.85) | LOXL2ST14MAOB | |
| SCHEMBL21063 | 0.85 | — | — | |
| SCHEMBL506985 | 0.85 | ST14 (0.73) | LOXL2ST14MAOBTAAR1 | |
| SCHEMBL184274 | 0.85 | ST14 (0.55) | LOXL2ST14MAOB | |
| Water SCHEMBL919765 | 0.83 | ST14 (0.53) | LOXL2ST14MAOB | |
| Hydrochloric Acid SCHEMBL922110 | 0.83 | ST14 (0.53) | LOXL2ST14MAOB | |
| Iodide SCHEMBL20838270 | 0.83 | LOXL2 (0.94) | LOXL2MAOBTAAR1IDO1AGXT | |
| Bromide SCHEMBL31513710 | 0.83 | LOXL2 (0.94) | LOXL2MAOBTAAR1IDO1AGXT | |
| Hydrochloric Acid SCHEMBL3847812 | 0.83 | LOXL2 (0.94) | LOXL2MAOBTAAR1IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9833768-B2 | Affinity reagents for protein purification | IMPOSSIBLE FOODS INC. (US) | 2017-12-05 | — | — | US | claimed |
| US-20170320041-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | IMPOSSIBLE FOODS INC. | 2017-11-09 | — | — | US | claimed |
| US-9737875-B2 | Affinity reagents for protein purification | IMPOSSIBLE FOODS INC. (US) | 2017-08-22 | — | — | US | claimed |
| CN-102762556-A | Imidazo [1,2-a ] pyridine compounds and synthesis and use methods thereof | UNIV NOTRE DAME DU LAC | 2012-10-31 | — | — | CN | claimed |
| EP-2496578-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | University of Notre Dame du Lac (US) | 2012-09-12 | — | — | EP | claimed |
| US-20120220457-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | claimed |
| WO-2011057145-A2 | IMIDAZO[1,2-A] PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-05-12 | — | — | WO | claimed |
| WO-1994005642-A1 | INDAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | claimed |
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-02-07 | — | — | US | disclosed |
| US-10913737-B2 | Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-02-09 | — | — | US | disclosed |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-01-21 | — | — | US | disclosed |
| WO-2019173507-A1 | ANTIBACTERIAL AGENTS : ARYLALKYLCARBOXAMIDO PHLOROGLUCINOLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2019-09-12 | — | — | WO | disclosed |
| US-20180354944-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2018-12-13 | — | — | US | disclosed |
| US-9908876-B2 | Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2018-03-06 | — | — | US | disclosed |
| EP-1778634-A1 | ISOINDOLONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | AstraZeneca AB (SE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2007021308-A1 | METABOTROPIC GLUTAMATE-RECEPTOR-POTENTIATING ISOINDOLONES | ASTRAZENECA AB (SE) | 2007-02-22 | — | — | WO | disclosed |
| WO-2006020879-A1 | ISOINDOLONE COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS | ASTRAZENECA AB (SE) | 2006-02-23 | — | — | WO | disclosed |
| EP-0784612-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |
| WO-1994005642-A1 | INDAZOLE DERIVATIVES | CIBA-GEIGY AG (CH) | 1994-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913737-B2 | Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same | RIF1, PYCR1, PNMT | LOXL2 4577/4885ST14 3753/4885MAOB 1639/4885 |
| US-11572337-B2 | Antibacterial agents: arylalkylcarboxamido phloroglucinols | RNGTT, FBL, POLR1C | LOXL2 4206/4885ST14 888/4885MAOB 1629/4885 |
| US-20120220457-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | RIF1, PYCR1, PNMT | LOXL2 4577/4885ST14 3753/4885MAOB 1639/4885 |
| US-20180354944-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | RIF1, PYCR1, PNMT | LOXL2 4577/4885ST14 3753/4885MAOB 1639/4885 |
| US-20170320041-A1 | AFFINITY REAGENTS FOR PROTEIN PURIFICATION | RAB5IF, MRPL21, RPS27A | LOXL2 3343/4885ST14 2552/4885MAOB 4408/4885 |
| US-20210017126-A1 | Antibacterial Agents: Arylalkylcarboxamido Phloroglucinols | RNGTT, FBL, POLR1C | LOXL2 4206/4885ST14 888/4885MAOB 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.