Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | LITAF | Q99732 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441668 | 0.84 | GAA (0.41) | PDE5ATNFLITAFMAPTG6PD | |
| SCHEMBL441685 | 0.80 | ACHE (0.35) | MAPTPOLBALDH1A1KMT2AKDM4E | |
| SCHEMBL438876 | 0.79 | BCHE (0.43) | MAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL435849 | 0.75 | HTR1A (0.44) | NSD2CASP6EP300 | |
| SCHEMBL20292984 | 0.75 | NSD2 (0.40) | TNFLITAFMAPTNSD2CASP6 | |
| SCHEMBL436999 | 0.73 | NQO2 (0.36) | MAPTNPSR1POLBL3MBTL1NSD2 | |
| SCHEMBL21358444 | 0.71 | PDPK1 (0.47) | MAPTNPSR1SRCPDPK1CSF1R | |
| SCHEMBL16047636 | 0.71 | MAPT (0.53) | MAPTNPSR1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL30254383 | 0.71 | MAPT (0.53) | MAPTNPSR1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL436601 | 0.70 | KMT2A (0.33) | POLBALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |