Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.35 |
| ▸ | BCHE | P06276 | 5/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435828 | 0.83 | ACHE (0.39) | ACHEGRIN1GRIN2ABCHEUHRF1 | |
| SCHEMBL439580 | 0.83 | BCHE (0.40) | ACHEGRIN1GRIN2ABCHEMAP3K14 | |
| SCHEMBL436945 | 0.83 | KDM4E (0.45) | UHRF1POLBKDM4EALDH1A1RAD52 | |
| SCHEMBL438876 | 0.83 | BCHE (0.43) | ACHEGRIN1GRIN2ABCHETP53 | |
| SCHEMBL436963 | 0.80 | PDE5A (0.38) | POLBKDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL436601 | 0.77 | KMT2A (0.33) | ACHEGRIN1GRIN2ABCHEPOLB | |
| SCHEMBL436954 | 0.75 | HAVCR2 (0.54) | SLC2A1TP53CYP3A4POLBKDM4E | |
| SCHEMBL438361 | 0.74 | ALDH1A1 (0.36) | ACHEGRIN1GRIN2ABCHEUHRF1 | |
| SCHEMBL439801 | 0.73 | ACHE (0.37) | ACHEGRIN1GRIN2ABCHEUHRF1 | |
| SCHEMBL441701 | 0.72 | ALDH1A1 (0.43) | POLBKDM4EALDH1A1RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |