Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441217 | 0.84 | KDM4E (0.36) | KMT2AKDM4EALDH1A1POLBRAD52 | |
| SCHEMBL438361 | 0.84 | ALDH1A1 (0.36) | KMT2AKDM4EALDH1A1POLBRAD52 | |
| SCHEMBL436945 | 0.83 | KDM4E (0.45) | KMT2AKDM4EALDH1A1POLBRAD52 | |
| SCHEMBL438876 | 0.83 | BCHE (0.43) | KMT2AKDM4EALDH1A1DYRK1AHTT | |
| SCHEMBL437542 | 0.80 | KDM4E (0.33) | KMT2AKDM4EALDH1A1POLBRAD52 | |
| SCHEMBL441685 | 0.77 | ACHE (0.35) | KMT2AKDM4EALDH1A1POLBRAD52 | |
| SCHEMBL435828 | 0.76 | ACHE (0.39) | KMT2AKDM4EALDH1A1POLBRAD52 | |
| SCHEMBL436971 | 0.75 | HAVCR2 (0.61) | KMT2AKDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL440009 | 0.73 | HAVCR2 (0.38) | KMT2AALDH1A1MEN1HAVCR2 | |
| SCHEMBL17981002 | 0.73 | KMT2A (0.40) | KMT2AKDM4EALDH1A1POLBDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |