Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 5/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048114 | 0.84 | EPAS1 (0.37) | EPAS1DRD2DRD4DRD3DRD1 | |
| SCHEMBL12381189 | 0.83 | CA1 (0.40) | EPAS1DRD2DRD4DRD3DRD1 | |
| SCHEMBL25353653 | 0.82 | ALPL (0.36) | EPAS1DRD2DRD4DRD3ALPL | |
| SCHEMBL2296015 | 0.81 | L3MBTL1 (0.38) | PTGS1PTGS2 | |
| SCHEMBL31204476 | 0.80 | TSHR (0.46) | EPAS1PDE4APDE4CPDE4DPTGS1 | |
| SCHEMBL19971751 | 0.79 | PTPN1 (0.39) | PDE4APDE4CPDE4DALPLADORA2A | |
| SCHEMBL1411551 | 0.79 | PTGS1 (0.46) | EPAS1PTGS1PTGS2 | |
| SCHEMBL8359389 | 0.78 | EPAS1 (0.46) | EPAS1PDE4APDE4CPDE4DPTGS1 | |
| SCHEMBL1713611 | 0.78 | DRD2 (0.40) | DRD2DRD4DRD3CHRM1ADORA2A | |
| SCHEMBL29607374 | 0.78 | DRD2 (0.40) | DRD2DRD4DRD3CHRM1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891484-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-10-17 | — | — | CN | disclosed |
| US-20090087721-A1 | SURFACE-MODIFIED CARBON MATERIAL AND METHOD FOR PRODUCING THE SAME | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090087721-A1 | SURFACE-MODIFIED CARBON MATERIAL AND METHOD FOR PRODUCING THE SAME | CD63, SCO2, CD99 | EPAS1 4768/4885DRD2 2797/4885DRD4 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.