Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611563 | 0.88 | HSD11B1 (0.37) | L3MBTL1HSD11B1CA1CA2CA12 | |
| SCHEMBL17048114 | 0.83 | EPAS1 (0.37) | HSD11B1CA1CA2SMN1; SMN2 | |
| SCHEMBL12381189 | 0.82 | CA1 (0.40) | HSD11B1CA1CA2CA9GAA | |
| SCHEMBL6935409 | 0.81 | CA12 (0.55) | L3MBTL1CA1CA2CA12CA7 | |
| SCHEMBL6938157 | 0.81 | CA12 (0.55) | L3MBTL1CA1CA2CA12CA7 | |
| SCHEMBL4370623 | 0.81 | EPAS1 (0.38) | PTGS1PTGS2 | |
| SCHEMBL25353653 | 0.81 | ALPL (0.36) | HSD11B1CA1CA2GAASMN1; SMN2 | |
| SCHEMBL16797507 | 0.80 | MAPK1 (0.33) | HSD11B1CA1CA2SMN1; SMN2KMT2A | |
| SCHEMBL29134970 | 0.80 | EPAS1 (0.43) | L3MBTL1CA1CA2CA12CA7 | |
| SCHEMBL5980992 | 0.80 | GAA (0.43) | L3MBTL1CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230087351-A1 | METHYL 2-ALLYL-1 -METHYL-3-OXOINDOLINE-2-CARBOXYLATE AND 9A-ALLYL-1,2,3,9A-TETRAHYDRO- 9H-PYRROLO[1,2-A]INDOL-9-ONE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS FLUORESCENT MARKERS FOR LABELLING OF DRUGS, AMINO ACIDS AN PROTEINS | UNIVERSITY OF SALFORD (GB) | 2023-03-23 | — | — | US | disclosed |
| CN-113683550-A | Synthesis method of N- (cyano (2-cyano substituted phenyl) methyl) substituted tertiary amine | 兰州大学 | 2021-11-23 | — | — | CN | disclosed |
| WO-2021116686-A1 | METHYL 2-ALLYL-1 -METHYL-3-OXOINDOLINE-2-CARBOXYLATE AND 9A-ALLYL-1,2,3,9A-TETRAHYDRO-9H-PYRROLO[1,2-A]INDOL-9-ONE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS FLUORESCENT MARKERS FOR LABELLING OF DRUGS, AMINO ACIDS AN PROTEINS | UNIVERSITY OF LANCASTER (GB) | 2021-06-17 | — | — | WO | disclosed |
| US-10153450-B2 | Fused aromatic derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2018-12-11 | — | — | US | disclosed |
| EP-2213641-B1 | FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | IDEMITSU KOSAN CO (JP) | 2018-05-16 | — | — | EP | disclosed |
| US-20140061628-A1 | FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2014-03-06 | — | — | US | disclosed |
| US-8623520-B2 | Fused aromatic derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2014-01-07 | — | — | US | disclosed |
| US-8623520-B2 | Fused aromatic derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2014-01-07 | — | — | US | disclosed |
| US-8481517-B2 | Pyrrolidine compounds,pharmaceutical compositions containing the same, devices containing the same, and methods of treating asthma or chronic obstructive pulmonary disease by administering the same | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-07-09 | — | — | US | disclosed |
| EP-2531516-A2 | PREGNANE COMPOUNDS CONDENSED IN POSITION 16,17 WITH A PYROLIDINE RING WITH GLUCOCORTICOID ACTIVITY | Chiesi Farmaceutici S.p.A. (IT) | 2012-12-12 | — | — | EP | disclosed |
| US-20110201580-A1 | PYRROLIDINE DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-08-18 | — | — | US | disclosed |
| WO-2011095535-A2 | PYRROLIDINE DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-08-11 | — | — | WO | disclosed |
| WO-2011095535-A2 | PYRROLIDINE DERIVATIVES | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-08-11 | — | — | WO | disclosed |
| US-20100295030-A1 | FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. | 2010-11-25 | — | — | US | disclosed |
| US-20100295030-A1 | FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. | 2010-11-25 | — | — | US | disclosed |
| EP-2213641-A1 | FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10153450-B2 | Fused aromatic derivative and organic electroluminescence device using the same | NRAS, RSU1, RAP1A | L3MBTL1 490/4885HSD11B1 3753/4885CA1 2633/4885 |
| US-20100295030-A1 | FUSED AROMATIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | NRAS, RSU1, RAP1A | L3MBTL1 490/4885HSD11B1 3753/4885CA1 2633/4885 |
| US-20110201580-A1 | PYRROLIDINE DERIVATIVES | IL5, TSLP, NR3C1 | L3MBTL1 4879/4885HSD11B1 38/4885CA1 3908/4885 |
| US-20230087351-A1 | METHYL 2-ALLYL-1 -METHYL-3-OXOINDOLINE-2-CARBOXYLATE AND 9A-ALLYL-1,2,3,9A-TETRAHYDRO- 9H-PYRROLO[1,2-A]INDOL-9-ONE DERIVATIVES AND RELATED COMPOUNDS FOR USE AS FLUORESCENT MARKERS FOR LABELLING OF DRUGS, AMINO ACIDS AN PROTEINS | INMT, AZI2, OPRD1 | L3MBTL1 2863/4885HSD11B1 3222/4885CA1 3145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.