Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.33 |
| ▸ | PNLIP | P16233 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375795 | 0.93 | TBXA2R (0.34) | SCN9APRSS1TBXA2RCA12CA1 | |
| SCHEMBL4371687 | 0.93 | SMN1; SMN2 (0.36) | SCN9APRSS1CA12CA1CA2 | |
| SCHEMBL4372245 | 0.91 | TBXA2R (0.39) | SCN9ATBXA2R | |
| SCHEMBL4377327 | 0.90 | F2 (0.39) | MRGPRX1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL1804010 | 0.90 | CARM1 (0.35) | MRGPRX1PRSS1CARM1PRMT6TBXA2R | |
| SCHEMBL1799336 | 0.89 | F2 (0.34) | MRGPRX1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL1800832 | 0.83 | F2 (0.37) | SCN9APRSS1F2PRSS2PRSS3 | |
| SCHEMBL3874559 | 0.83 | NPY4R (0.36) | — | |
| SCHEMBL1799060 | 0.82 | SLC9A3 (0.36) | — | |
| SCHEMBL1800587 | 0.82 | SLC9A3 (0.33) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461313-B1 | HUMAN ADAM-10 INHIBITORS | EXELIXIS INC (US) | 2009-08-05 | — | — | EP | claimed |
| EP-1461313-B1 | HUMAN ADAM-10 INHIBITORS | EXELIXIS INC (US) | 2009-08-05 | — | — | EP | disclosed |