Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 4/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 4/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372704 | 0.86 | HPGDS (0.41) | HPGDSWNT3AFYNMLNRTRPM8 | |
| SCHEMBL3879768 | 0.85 | WNT3A (0.40) | HPGDSWNT3AMLNR | |
| SCHEMBL4372679 | 0.76 | MMP2 (0.47) | HPGDSMMP2MMP9 | |
| SCHEMBL4377641 | 0.73 | MMP2 (0.40) | HPGDSWNT3AMLNRMMP2MMP9 | |
| SCHEMBL6864486 | 0.73 | WNT3A (0.39) | HPGDSWNT3AMLNRTRPM8 | |
| SCHEMBL3879230 | 0.72 | MMP2 (0.44) | DPP9MMP2MMP9 | |
| SCHEMBL4542075 | 0.72 | HPGDS (0.42) | HPGDSWNT3AFYNMLNR | |
| SCHEMBL1800259 | 0.70 | HPGDS (0.39) | HPGDSWNT3AMLNRMMP2MMP9 | |
| SCHEMBL3871098 | 0.70 | HPGDS (0.37) | HPGDSMMP2MMP9CTSLCTSB | |
| SCHEMBL4374530 | 0.70 | MMP2 (0.36) | HPGDSMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461313-B1 | HUMAN ADAM-10 INHIBITORS | EXELIXIS INC (US) | 2009-08-05 | — | — | EP | claimed |
| EP-1461313-B1 | HUMAN ADAM-10 INHIBITORS | EXELIXIS INC (US) | 2009-08-05 | — | — | EP | disclosed |