Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.36 |
| ▸ | MMP9 | P14780 | 5/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | MMP12 | P39900 | 3/20 | 0.33 |
| ▸ | MMP14 | P50281 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HPN | P05981 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369622 | 0.93 | MMP2 (0.35) | MMP2MMP9HPGDSMMP1MAP4K4 | |
| SCHEMBL3871098 | 0.88 | HPGDS (0.37) | MMP2MMP9HPGDSMAP4K4F2 | |
| SCHEMBL1797052 | 0.88 | F2 (0.37) | PTGS2MAP4K4F2 | |
| SCHEMBL4377641 | 0.88 | MMP2 (0.40) | MMP2MMP9HPGDSMMP1MMP3 | |
| SCHEMBL7174227 | 0.86 | CA2 (0.34) | MMP2MMP9HPGDSMMP8MMP14 | |
| SCHEMBL4373799 | 0.81 | MMP2 (0.38) | MMP2MMP9MMP8MMP12MMP14 | |
| SCHEMBL1800984 | 0.81 | ADAM17 (0.40) | MMP2MMP9MMP12MMP14MMP1 | |
| SCHEMBL4374166 | 0.79 | MMP2 (0.45) | MMP2MMP9MMP8MMP12MMP14 | |
| SCHEMBL1800259 | 0.77 | HPGDS (0.39) | MMP2MMP9HPGDSMMP8MMP14 | |
| SCHEMBL4372679 | 0.76 | MMP2 (0.47) | MMP2MMP9HPGDSMMP12MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461313-B1 | HUMAN ADAM-10 INHIBITORS | EXELIXIS INC (US) | 2009-08-05 | — | — | EP | claimed |