Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436942 | 0.87 | HAVCR2 (0.41) | CCR1CCR5CCR8HAVCR2DYRK1A | |
| SCHEMBL441974 | 0.83 | HAVCR2 (0.38) | CCR1CCR5CCR8HAVCR2DYRK1A | |
| SCHEMBL437599 | 0.79 | CCR1 (0.42) | CCR1CCR5CCR8HAVCR2NOS3 | |
| SCHEMBL442075 | 0.79 | HAVCR2 (0.46) | HAVCR2LMNAPOLBCYP1A2CYP2A6 | |
| SCHEMBL438820 | 0.76 | HAVCR2 (0.39) | HAVCR2LMNAPOLBDYRK1AACHE | |
| SCHEMBL438308 | 0.75 | HAVCR2 (0.57) | CCR1CCR5CCR8HAVCR2CYP3A4 | |
| SCHEMBL436692 | 0.74 | POLB (0.38) | CCR1CCR5CCR8HAVCR2CYP3A4 | |
| SCHEMBL437482 | 0.73 | CYP3A4 (0.35) | CCR1CCR5CCR8HAVCR2CYP3A4 | |
| SCHEMBL13539131 | 0.72 | CCR1 (0.78) | CCR1CCR5CCR8NOS3NOS2 | |
| SCHEMBL440009 | 0.72 | HAVCR2 (0.38) | CCR1CCR5CCR8HAVCR2PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |