Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BCL6 | P41182 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437482 | 0.84 | CYP3A4 (0.35) | HAVCR2CYP3A4 | |
| SCHEMBL439672 | 0.82 | DYRK1A (0.35) | HAVCR2SMN1; SMN2NR4A2DYRK1A | |
| SCHEMBL440283 | 0.80 | DYRK1A (0.39) | DYRK1AGAA | |
| SCHEMBL439519 | 0.80 | DYRK1A (0.39) | DYRK1AGAA | |
| SCHEMBL440068 | 0.76 | HAVCR2 (0.63) | HAVCR2SMN1; SMN2TSHR | |
| SCHEMBL436692 | 0.74 | POLB (0.38) | HAVCR2DYRK1ACYP3A4 | |
| SCHEMBL439646 | 0.74 | HAVCR2 (0.32) | HAVCR2DYRK1A | |
| SCHEMBL441707 | 0.71 | HAVCR2 (0.63) | HAVCR2SMN1; SMN2NR4A2DYRK1AACHE | |
| SCHEMBL438820 | 0.71 | HAVCR2 (0.39) | HAVCR2SMN1; SMN2NR4A2DYRK1AACHE | |
| SCHEMBL436747 | 0.69 | CYP3A4 (0.32) | DYRK1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |