Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441707 | 0.83 | HAVCR2 (0.63) | HAVCR2ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL437847 | 0.79 | CCR1 (0.42) | HAVCR2RAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL437767 | 0.79 | HAVCR2 (0.46) | HAVCR2ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL441422 | 0.79 | HAVCR2 (0.46) | HAVCR2SMN1; SMN2PARP1ACHENR4A2 | |
| SCHEMBL441701 | 0.79 | ALDH1A1 (0.43) | HAVCR2RAB9AALDH1A1KDM4EPSMD14 | |
| SCHEMBL437574 | 0.78 | PARP1 (0.45) | HAVCR2PARP1NR4A2 | |
| SCHEMBL436008 | 0.78 | HTR1A (0.44) | HAVCR2ALDH1A1KDM4EHTR1AADRA1D | |
| SCHEMBL440440 | 0.78 | HAVCR2 (0.47) | HAVCR2RAB9APARP1ACHENR4A2 | |
| SCHEMBL436942 | 0.76 | HAVCR2 (0.41) | HAVCR2RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL18436374 | 0.76 | AXL (0.46) | RAB9ASMN1; SMN2PARP1HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |