SCHEMBL43754

SCHEMBL43754

Nc1ccc(B2Oc3ccccc3O2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
CYP3A4 P08684 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
HSD17B10 Q99714 2/20 0.37
TAAR1 Q96RJ0 2/20 0.37
MAPT P10636 7/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 5/20 0.34
KDM4E B2RXH2 3/20 0.34
MAOA P21397 4/20 0.33
MAOB P27338 4/20 0.33
RAB9A P51151 4/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HTT P42858 2/20 0.33
CYP2D6 P10635 1/20 0.33
P2RX4 Q99571 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1453305 0.80 LPL (0.35) TDP1ALDH1A1LPLLIPG
SCHEMBL13429479 0.77 AHR (0.40) TDP1MEN1KMT2AALDH1A1LPL
SCHEMBL15976050 0.77 ACHE (0.38) TSHRTDP1ALDH1A1MAOBRAB9A
SCHEMBL2073992 0.77 TSHR (0.38) TSHRMEN1KMT2AMAOAMAOB
SCHEMBL12062036 0.77 LPL (0.42) MAOBCYP1A2CYP19A1LPLLIPG
SCHEMBL3197481 0.77 CYP3A4 (0.42) TSHRCYP3A4TDP1MAPTMEN1
SCHEMBL13855240 0.76 LPL (0.42) LPLLIPG
SCHEMBL13309430 0.76 MAPT (0.40) HSD17B10MAPTSMN1; SMN2LPLLIPG
SCHEMBL13855245 0.76 ALDH1A1 (0.37) CYP3A4TDP1MAPTMEN1KMT2A
SCHEMBL12513168 0.74 MEN1 (0.38) CYP3A4TDP1HSD17B10MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507262-B2 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY (US) 2009-03-24 US claimed
EP-2018146-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS The Procter and Gamble Company (US) 2009-01-28 EP claimed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 US claimed
WO-2007102126-A2 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2007-09-13 WO claimed
US-10504732-B2 Impurity diffusion agent composition and method for manufacturing semiconductor substrate TOKYO OHKA KOGYO CO, LTD. (JP) 2019-12-10 US disclosed
US-20180182624-A1 IMPURITY DIFFUSION AGENT COMPOSITION AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE TOKYO OHKA KOGYO CO., LTD. (JP) 2018-06-28 US disclosed
US-20180182624-A1 IMPURITY DIFFUSION AGENT COMPOSITION AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE TOKYO OHKA KOGYO CO., LTD. (JP) 2018-06-28 US disclosed
US-8299290-B2 Boron containing functionalizing agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-10-30 US disclosed
US-8299290-B2 Boron containing functionalizing agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-10-30 US disclosed
WO-2012025760-A1 PROCESS FOR THE BORYLATION OF ARENES AND HETEROARYLS THE UNIVERSITY OF MANCHESTER (GB) 2012-03-01 WO disclosed
US-20120029234-A1 BORON CONTAINING FUNCTIONALIZING AGENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-02-02 US disclosed
US-20120029234-A1 BORON CONTAINING FUNCTIONALIZING AGENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-02-02 US disclosed
US-8063152-B2 Boron containing functionalizing agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2011-11-22 US disclosed
US-8063152-B2 Boron containing functionalizing agent THE GOODYEAR TIRE & RUBBER COMPANY (US) 2011-11-22 US disclosed
US-7678158-B2 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY (US) 2010-03-16 US disclosed
US-20090229729-A1 BORON CONTAINING FUNCTIONALIZING AGENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-09-17 US disclosed
US-20090229729-A1 BORON CONTAINING FUNCTIONALIZING AGENT THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-09-17 US disclosed
US-20090144914-A1 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS LIM MU LLL 2009-06-11 US disclosed
US-7507262-B2 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY (US) 2009-03-24 US disclosed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180182624-A1 IMPURITY DIFFUSION AGENT COMPOSITION AND METHOD FOR MANUFACTURING SEMICONDUCTOR SUBSTRATE SLC43A1, SAMHD1, SNRPD2 TSHR 4456/4885CYP3A4 2433/4885TDP1 943/4885
US-20090229729-A1 BORON CONTAINING FUNCTIONALIZING AGENT BOLA2; BOLA2B, RBBP4, BRPF1 TSHR 1203/4885CYP3A4 1454/4885TDP1 1843/4885
US-20120029234-A1 BORON CONTAINING FUNCTIONALIZING AGENT BOLA2; BOLA2B, RBBP4, BRPF1 TSHR 1203/4885CYP3A4 1454/4885TDP1 1843/4885
US-20090144914-A1 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS KRT18, AKR7A2, AKR1C4 TSHR 2810/4885CYP3A4 2154/4885TDP1 1995/4885
US-10504732-B2 Impurity diffusion agent composition and method for manufacturing semiconductor substrate SLC43A1, SAMHD1, SNRPD2 TSHR 4456/4885CYP3A4 2433/4885TDP1 943/4885
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions KRT18, AKR7A2, AKR1C4 TSHR 2810/4885CYP3A4 2154/4885TDP1 1995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.