Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL28175895 | 0.98 | KIF11 (0.45) | KIF11CA1CA2CA9MAOB | |
| SCHEMBL10627367 | 0.86 | KIF11 (0.33) | KIF11CA1CA2CA9 | |
| SCHEMBL29116660 | 0.86 | PDE2A (0.39) | KIF11CA1CA2CA9ALDH1A1 | |
| SCHEMBL24990 | 0.83 | ESR1 (0.45) | KIF11 | |
| SCHEMBL17042662 | 0.81 | NPC1 (0.31) | KIF11ALDH1A1 | |
| SCHEMBL24787 | 0.80 | CA1 (0.32) | CA1CA2CA9MAOBALDH1A1 | |
| SCHEMBL28868994 | 0.79 | — | — | |
| SCHEMBL28868996 | 0.78 | AR (0.31) | — | |
| SCHEMBL1555244 | 0.77 | HPGD (0.41) | KIF11CA1CA2CA9ALDH1A1 | |
| SCHEMBL15879800 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117165078-A | Cyanate resin with low dielectric loss suitable for winding forming process, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2023-12-05 | — | — | CN | claimed |
| CN-117165078-A | Cyanate resin with low dielectric loss suitable for winding forming process, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2023-12-05 | — | — | CN | disclosed |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-09 | — | — | US | disclosed |
| US-20220135517-A1 | METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND | FUJIFILM CORPORATION (JP) | 2022-05-05 | — | — | US | disclosed |
| US-20180022714-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC. | 2018-01-25 | — | — | US | disclosed |
| CN-107303293-A | Application of the isosulfocyanate compound in preventing and/or treating hyperbilirubinemia | 无锡杰西医药股份有限公司 | 2017-10-31 | — | — | CN | disclosed |
| CN-107303292-A | Application of the isosulfocyanate compound in preventing and/or treating hyperlipemia | 无锡杰西医药股份有限公司 | 2017-10-31 | — | — | CN | disclosed |
| US-9725421-B2 | Substituted quinoxalines as B-raf kinase inhibitors | NEUPHARMA, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160009663-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC. | 2016-01-14 | — | — | US | disclosed |
| US-9233961-B2 | Compounds and compositions for the treatment of parasitic diseases | NOVARTIS AG (CH) | 2016-01-12 | — | — | US | disclosed |
| US-20140275013-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2014-09-18 | — | — | US | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009663-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | BRAF, PIK3CA, PLK1 | KIF11 1225/4885CA1 2493/4885CA2 948/4885 |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | ATG7, GOT1, LIPC | KIF11 3328/4885CA1 4805/4885CA2 4828/4885 |
| US-20180022714-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | BRAF, PIK3CA, PLK1 | KIF11 1225/4885CA1 2493/4885CA2 948/4885 |
| US-20220135517-A1 | METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND | PARG, PTGIS, MT-ATP8 | KIF11 1273/4885CA1 2542/4885CA2 1471/4885 |
| US-20140275013-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | TYR, TBCA, MAPT | KIF11 2068/4885CA1 2043/4885CA2 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.