SCHEMBL437690

SCHEMBL437690

C=C(C)C(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.55
HSD17B10 Q99714 1/20 0.55
ABCC9 O60706 1/20 0.54
ABCC8 Q09428 1/20 0.54
KCNJ11 Q14654 1/20 0.54
KCNJ8 Q15842 1/20 0.54
RXFP1 Q9HBX9 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
NPC1 O15118 1/20 0.52
TP53 P04637 1/20 0.52
MAPK1 P28482 1/20 0.52
RAB9A P51151 1/20 0.52
TRPV4 Q9HBA0 1/20 0.52
KMT2A Q03164 3/20 0.51
LMNA P02545 3/20 0.51
ALDH1A1 P00352 3/20 0.51
PKM P14618 2/20 0.51
ATM Q13315 1/20 0.51
TSHR P16473 1/20 0.51
MEN1 O00255 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396051 0.83 MEN1 (0.57) MAPTABCC9ABCC8KCNJ11KCNJ8
SCHEMBL7607384 0.83 PKM (0.59) MAPTRXFP1MAPK1KMT2ALMNA
SCHEMBL7570377 0.83 GAA (0.69) MAPTHSD17B10ABCC9ABCC8KCNJ11
SCHEMBL397453 0.82 KMT2A (0.59) MAPTSMN1; SMN2NPC1RAB9AKMT2A
SCHEMBL16882784 0.82 ABCC9 (0.46) MAPTHSD17B10ABCC9ABCC8KCNJ11
SCHEMBL21086837 0.81 TGM2 (0.60) RXFP1
SCHEMBL691748 0.81 RXFP1 (0.57) MAPTRXFP1KMT2AALDH1A1PKM
SCHEMBL439393 0.80 RXFP1 (0.74) MAPTHSD17B10RXFP1SMN1; SMN2NPC1
SCHEMBL3463275 0.80 RXFP1 (0.56) MAPTRXFP1KMT2AALDH1A1PKM
SCHEMBL202716 0.80 CA1 (0.69) RXFP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102540713-A Resin composition for laser engraving, relief printing plate precursor for laser engraving and process for producing same, and process for making relief printing plate FUJIFILM CORP 2012-07-04 CN disclosed
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-06-14 US disclosed
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
EP-1972440-B1 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM CORP (JP) 2010-06-23 EP disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1972440-A2 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120146264-A1 RESIN COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, AND PROCESS FOR MAKING RELIEF PRINTING PLATE EIF3L, EIF2B1, EIF2B5 MAPT 1418/4885HSD17B10 2408/4885ABCC9 4585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.