Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378227 | 1.00 | TDP1 (0.36) | TDP1LMNACYP2C9 | |
| SCHEMBL5398400 | 1.00 | TDP1 (0.36) | TDP1LMNACYP2C9 | |
| SCHEMBL14598562 | 1.00 | TDP1 (0.36) | TDP1LMNACYP2C9 | |
| SCHEMBL7955675 | 0.84 | LMNA (0.43) | TDP1LMNACYP2C9 | |
| SCHEMBL7955673 | 0.84 | LMNA (0.43) | TDP1LMNACYP2C9 | |
| SCHEMBL14755887 | 0.79 | SLC6A3 (0.38) | TDP1 | |
| SCHEMBL4420172 | 0.79 | SLC6A3 (0.38) | TDP1 | |
| SCHEMBL20692827 | 0.78 | TDP1 (0.32) | TDP1 | |
| SCHEMBL10607812 | 0.77 | NCF1 (0.33) | TDP1 | |
| SCHEMBL13894567 | 0.75 | BRD4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713800-B1 | METHOD FOR PRODUCING A 2-(ETHOXYMETHYL)TROPANE DERIVATIVE | NEUROSEARCH AS (DK) | 2009-11-18 | — | — | EP | claimed |
| US-7544802-B2 | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | NEUROSEARCH A/S (DK) | 2009-06-09 | — | — | US | claimed |
| US-20050171145-A1 | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-08-04 | — | — | US | claimed |
| CN-1910180-B | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | NEUROSEARCH AS | 2010-05-12 | — | — | CN | disclosed |
| CN-1910180-B | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | NEUROSEARCH AS | 2010-05-12 | — | — | CN | disclosed |
| US-7544802-B2 | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | NEUROSEARCH A/S (DK) | 2009-06-09 | — | — | US | disclosed |
| US-7544802-B2 | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | NEUROSEARCH A/S (DK) | 2009-06-09 | — | — | US | disclosed |
| CN-1910180-A | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | BOEHRINGER INGELHEIM INT (DK) | 2007-02-07 | — | — | CN | disclosed |
| CN-1910180-A | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | BOEHRINGER INGELHEIM INT (DK) | 2007-02-07 | — | — | CN | disclosed |
| EP-1713800-A2 | METHOD FOR PRODUCING A 2-(ETHOXYMETHYL)TROPANE DERIVATIVE | NEUROSEARCH A/S (DK) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073228-A8 | METHOD FOR PRODUCING A 2-(ETHOXYMETHYL)TROPANE DERIVATIVE | BOEHRINGER INGELHEIM INT (DE) | 2005-10-27 | — | — | WO | disclosed |
| WO-2005073228-A1 | METHOD FOR PRODUCING A 2-(ETHOXYMETHYL)TROPANE DERIVATIVE | NEUROSEARCH A/S (DK) | 2005-08-11 | — | — | WO | disclosed |
| US-20050171145-A1 | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-08-04 | — | — | US | disclosed |
| US-20050171145-A1 | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171145-A1 | Process for the preparation of 2-(ethoxymethyl)-tropane derivatives | ADRB2, TPM3, TPM4 | TDP1 220/4885LMNA 2476/4885CYP2C9 232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.