Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.53 |
| ▸ | NMT2 | O60551 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437781 | 0.89 | MAPT (0.61) | NMT1NMT2MAPTALDH1A1LMNA | |
| SCHEMBL438203 | 0.88 | MAPT (0.62) | NMT1NMT2MAPTALDH1A1LMNA | |
| SCHEMBL620385 | 0.87 | NMT1 (0.53) | NMT1NMT2MAPTALDH1A1LMNA | |
| SCHEMBL621322 | 0.86 | NMT1 (0.54) | NMT1NMT2MAPTALDH1A1LMNA | |
| SCHEMBL618676 | 0.86 | MAPT (0.53) | NMT1NMT2MAPTALDH1A1LMNA | |
| SCHEMBL619241 | 0.84 | NMT1 (0.58) | NMT1NMT2MAPTALDH1A1LMNA | |
| SCHEMBL618409 | 0.84 | ALDH1A1 (0.51) | NMT1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL438198 | 0.84 | MAPK1 (0.63) | NMT1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL437947 | 0.83 | KMT2A (0.53) | NMT1NMT2MAPTALDH1A1LMNA | |
| SCHEMBL441687 | 0.81 | KMT2A (0.62) | NMT1NMT2MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | disclosed |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | FIREMENICH INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |
| EP-2552207-B1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED (US) | 2019-08-21 | — | — | EP | disclosed |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2019-07-11 | — | — | US | disclosed |
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-9902737-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2018-02-27 | — | — | US | disclosed |
| CN-106107406-A | Improve the method for the stability of sweetness enhancers and comprise the compositions of stable sweetness enhancers | 赛诺米克斯公司 | 2016-11-16 | — | — | CN | disclosed |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2016-09-01 | — | — | US | disclosed |
| CN-103153096-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 赛诺米克斯公司 | 2016-08-03 | — | — | CN | disclosed |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| EP-2603098-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | Senomyx, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| CN-103153096-A | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | SENOMYX INC | 2013-06-12 | — | — | CN | disclosed |
| CN-102933081-A | Sweet flavor modifier | SENOMYX INC | 2013-02-13 | — | — | CN | disclosed |
| EP-2552207-A1 | SWEET FLAVOR MODIFIER | Senomyx, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2012021837-A2 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | SENOMYX, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011123693-A1 | SWEET FLAVOR MODIFIER | SENOMYX, INC. (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | NMT1 3466/4885NMT2 3241/4885MAPT 1864/4885 |
| US-20120041078-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | NMT1 3466/4885NMT2 3241/4885MAPT 1864/4885 |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | NMT1 1072/4885NMT2 1251/4885MAPT 3167/4885 |
| US-20140128481-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | NMT1 1072/4885NMT2 1251/4885MAPT 3167/4885 |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | NMT1 3466/4885NMT2 3241/4885MAPT 1864/4885 |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | NMT1 3466/4885NMT2 3241/4885MAPT 1864/4885 |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | NMT1 1072/4885NMT2 1251/4885MAPT 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.