Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 2/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.32 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4382952 | 0.91 | OPRD1 (0.38) | GHSRADORA1P2RX7MEN1KMT2A | |
| SCHEMBL4369760 | 0.88 | GHSR (0.48) | GHSRADORA1P2RX7DPP4CCKBR | |
| SCHEMBL867813 | 0.88 | LMNA (0.43) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL867814 | 0.88 | LMNA (0.43) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7856855 | 0.88 | LMNA (0.43) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL13759959 | 0.84 | ALDH1A1 (0.38) | GHSRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL868492 | 0.83 | GHSR (0.37) | GHSRP2RX7MEN1KMT2ADPP4 | |
| SCHEMBL868493 | 0.83 | GHSR (0.37) | GHSRP2RX7MEN1KMT2ADPP4 | |
| SCHEMBL4385374 | 0.80 | GHSR (0.40) | GHSRDPP4OPRD1 | |
| SCHEMBL4369742 | 0.80 | GHSR (0.48) | GHSRMEN1KMT2ADPP4OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077941-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2009-08-12 | — | — | EP | claimed |