Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11262505 | 0.98 | NNMT (0.48) | NNMTACHEPARP10CA2PARP1 | |
| Hydrochloric Acid SCHEMBL11270858 | 0.98 | NNMT (0.48) | NNMTACHEPARP10CA2PARP1 | |
| Iodide SCHEMBL11257085 | 0.98 | NNMT (0.48) | NNMTACHEPARP10CA2PARP1 | |
| SCHEMBL12849581 | 0.83 | TSHR (0.44) | CA2CA1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4381131 | 0.79 | NNMT (0.50) | NNMTACHEPARP10CA2PARP1 | |
| SCHEMBL4387671 | 0.78 | NNMT (0.48) | NNMTACHEPARP10CA2PARP1 | |
| SCHEMBL11545665 | 0.75 | CA2 (0.45) | NNMTACHEPARP10CA2PARP1 | |
| Terephthalamide SCHEMBL221067 | 0.70 | CYP3A4 (0.67) | NNMTPARP10CA2PARP1PARP4 | |
| Iodide SCHEMBL11262176 | 0.69 | ALDH1A1 (0.44) | NNMTACHEPARP10CA2PARP1 | |
| Iodide SCHEMBL11258786 | 0.68 | L3MBTL1 (0.45) | NNMTACHEPARP10CA2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790252-B2 | 2-fluorinated riboses and arabinoses and methods of use and synthesis | CORNELL UNIVERSITY (US) | 2017-10-17 | — | — | US | disclosed |
| US-8247445-B2 | Platinum complexes and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-08-21 | — | — | US | disclosed |
| US-20120108535-A1 | 2-FLUORINATED RIBOSES AND ARABINOSES AND METHODS OF USE AND SYNTHESIS | CORNELL UNIVERSITY (US) | 2012-05-03 | — | — | US | disclosed |
| US-20100316704-A1 | PLATINUM COMPLEXES AND METHODS OF USE | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-12-16 | — | — | US | disclosed |
| US-7759510-B2 | Platinum complexes and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-07-20 | — | — | US | disclosed |
| US-20090285884-A1 | Platinum Complexes and Methods of Use | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-11-19 | — | — | US | disclosed |
| US-7566798-B2 | Platinum complexes and methods of use | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100316704-A1 | PLATINUM COMPLEXES AND METHODS OF USE | CXCR3, POLI, ZC3HAV1 | NNMT 2461/4885ACHE 2639/4885PARP10 504/4885 |
| US-20090285884-A1 | Platinum Complexes and Methods of Use | CXCR3, POLI, ZC3HAV1 | NNMT 2461/4885ACHE 2639/4885PARP10 504/4885 |
| US-20120108535-A1 | 2-FLUORINATED RIBOSES AND ARABINOSES AND METHODS OF USE AND SYNTHESIS | SLC2A2, SLC29A2, DERA | NNMT 994/4885ACHE 2693/4885PARP10 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.