Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388471 | 0.92 | KDM4E (0.47) | L3MBTL1GAAKDM4EUGCG | |
| SCHEMBL4953302 | 0.89 | L3MBTL1 (0.53) | L3MBTL1GAAMEN1KMT2AKDM4E | |
| SCHEMBL4952879 | 0.88 | MEN1 (0.47) | L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL4383616 | 0.86 | MEN1 (0.47) | L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL4391863 | 0.83 | MAPT (0.40) | GAAMEN1KMT2A | |
| SCHEMBL4391283 | 0.83 | CYP2C9 (0.39) | L3MBTL1GAAMEN1KMT2AKDM4E | |
| SCHEMBL4385766 | 0.83 | RAB9A (0.51) | L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL2065962 | 0.82 | KMT2A (0.46) | MEN1KMT2AKDM4E | |
| SCHEMBL4377844 | 0.82 | MEN1 (0.45) | L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL4393751 | 0.81 | KDM4E (0.46) | L3MBTL1KDM4EUGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121635-A2 | SUBSTITUTED HETEROARYL PYRIDOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2009-11-25 | — | — | EP | claimed |
| WO-2008078196-A2 | SUBSTITUTED HETEROARYL PYRIDOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2008-07-03 | — | — | WO | claimed |
| EP-1939187-A1 | Substituted heteroaryl pyridopyrimidone derivatives | Sanofi-Aventis (FR) | 2008-07-02 | — | — | EP | claimed |
| US-8198287-B2 | Substituted heteroaryl pyridopyrimidone derivatives | SANOFI-AVENTIS (FR) | 2012-06-12 | — | — | US | disclosed |
| EP-2121635-A2 | SUBSTITUTED HETEROARYL PYRIDOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008078196-A2 | SUBSTITUTED HETEROARYL PYRIDOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2008-07-03 | — | — | WO | disclosed |
| EP-1939187-A1 | Substituted heteroaryl pyridopyrimidone derivatives | Sanofi-Aventis (FR) | 2008-07-02 | — | — | EP | disclosed |