Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 3/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396130 | 0.84 | S1PR1 (0.55) | HDAC1HDAC2S1PR2S1PR1S1PR3 | |
| SCHEMBL27792356 | 0.83 | CA2 (0.53) | SMN1; SMN2KDM4EALDH1A1PPARGALOX15 | |
| SCHEMBL4383896 | 0.82 | S1PR2 (0.61) | HDAC1HDAC2S1PR2S1PR1S1PR3 | |
| SCHEMBL4387213 | 0.80 | ALDH1A1 (0.42) | HDAC1HDAC2MRGPRX1SMN1; SMN2KDM4E | |
| SCHEMBL580128 | 0.79 | MRGPRX1 (0.56) | HDAC1HDAC2MRGPRX1SMN1; SMN2KDM4E | |
| SCHEMBL17521751 | 0.78 | MRGPRX1 (0.54) | HDAC1HDAC2MRGPRX1SMN1; SMN2KDM4E | |
| SCHEMBL8734316 | 0.75 | TSHR (0.55) | ALDH1A1ALOX15ALOX12LMNA | |
| SCHEMBL10760563 | 0.74 | KMT2A (0.59) | HDAC1HDAC2MRGPRX1SMN1; SMN2KDM4E | |
| SCHEMBL14907134 | 0.74 | TSHR (0.66) | HDAC1HDAC2HTT | |
| SCHEMBL8733965 | 0.74 | TSHR (0.54) | ALDH1A1ALOX15ALOX12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11160734-B2 | Personal care compositions comprising shaped abrasive particles | THE PROCTER & GAMBLE COMPANY (US) | 2021-11-02 | — | — | US | disclosed |
| EP-2720666-B1 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | PROCTER & GAMBLE (US) | 2019-03-20 | — | — | EP | disclosed |
| US-20170312190-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | PROCTER & GAMBLE (US) | 2017-11-02 | — | — | US | disclosed |
| US-9675531-B2 | Personal care compositions comprising shaped abrasive particles | THE PROCTER & GAMBLE COMPANY (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160367091-A9 | Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using | THE PROCTER & GAMBLE COMPANY | 2016-12-22 | — | — | US | disclosed |
| US-9271912-B2 | Personal care compositions comprising a pH tuneable gellant and methods of using | THE PROCTER & GAMBLE COMPANY (US) | 2016-03-01 | — | — | US | disclosed |
| EP-2720666-A2 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | The Procter and Gamble Company (US) | 2014-04-23 | — | — | EP | disclosed |
| EP-2717967-A2 | PERSONAL CARE COMPOSITIONS COMPRISING A pH TUNEABLE GELLANT AND METHODS OF USING | The Procter & Gamble Company (US) | 2014-04-16 | — | — | EP | disclosed |
| EP-2717966-A2 | PERSONAL CARE COMPOSITIONS COMPRISING A DI-AMIDO GELLANT AND METHODS OF USING | The Procter and Gamble Company (US) | 2014-04-16 | — | — | EP | disclosed |
| US-20130336902-A1 | Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using | FERNANDEZ PRIETO SUSANA (ES) | 2013-12-19 | — | — | US | disclosed |
| US-20130336903-A1 | Personal Care Compositions Comprising a pH Tuneable Gellant and Methods of Using | THE PROCTER & GAMBLE COMPANY | 2013-12-19 | — | — | US | disclosed |
| US-20130039961-A1 | Personal Care Compositions Comprising Shaped Abrasive Particles | THE PROCTER & GAMBLE COMPANY | 2013-02-14 | — | — | US | disclosed |
| WO-2012177757-A2 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012174091-A2 | PERSONAL CARE COMPOSITIONS COMPRISING A pH TUNEABLE GELLANT AND METHODS OF USING | THE PROCTER & GAMBLE COMPANY (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012174096-A2 | PERSONAL CARE COMPOSITIONS COMPRISING A DI-AMIDO GELLANT AND METHODS OF USING | THE PROCTER & GAMBLE COMPANY (US) | 2012-12-20 | — | — | WO | disclosed |
| EP-2120843-A1 | PERSONAL CARE KIT HAVING SKIN CARE COMPOSITIONS WITH A READILY PERCEPTIBLE DIFFERENCE | The Procter and Gamble Company (US) | 2009-11-25 | — | — | EP | disclosed |
| US-20090017080-A1 | PERSONAL CARE KIT HAVING SKIN CARE COMPOSITIONS WITH A READILY PERCEPTIBLE DIFFERENCE | THE PROCTER & GAMBLE COMPANY | 2009-01-15 | — | — | US | disclosed |
| WO-2008112964-A1 | PERSONAL CARE KIT HAVING SKIN CARE COMPOSITIONS WITH A READILY PERCEPTIBLE DIFFERENCE | THE PROCTER & GAMBLE COMPANY (US) | 2008-09-18 | — | — | WO | disclosed |
| EP-0837862-A1 | WARMING COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997002273-A1 | WARMING COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170312190-A1 | PERSONAL CARE COMPOSITIONS COMPRISING SHAPED ABRASIVE PARTICLES | POLR1C, PLOD3, C9 | HDAC1 1297/4885HDAC2 1291/4885MRGPRX1 2788/4885 |
| US-11160734-B2 | Personal care compositions comprising shaped abrasive particles | POLR1C, PLOD3, C9 | HDAC1 1297/4885HDAC2 1291/4885MRGPRX1 2788/4885 |
| US-20130336903-A1 | Personal Care Compositions Comprising a pH Tuneable Gellant and Methods of Using | ARGLU1, F12, GALR1 | HDAC1 1033/4885HDAC2 1963/4885MRGPRX1 435/4885 |
| US-20130336902-A1 | Personal Care Compositions Comprising a Di-Amido Gellant and Methods of Using | PARN, PARG, CUTA | HDAC1 1496/4885HDAC2 2781/4885MRGPRX1 940/4885 |
| US-20130039961-A1 | Personal Care Compositions Comprising Shaped Abrasive Particles | POLR1C, PLOD3, C9 | HDAC1 1297/4885HDAC2 1291/4885MRGPRX1 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.