Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | ATR | Q13535 | 3/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | CPT1A | P50416 | 1/20 | 0.37 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983393 | 0.72 | PAICS (0.43) | GPR119CKS1BSKP1SKP2 | |
| SCHEMBL3981387 | 0.71 | GPR119 (0.44) | RORCGPR119ATR | |
| SCHEMBL4387698 | 0.70 | RORC (0.47) | RORCGPR119ATR | |
| SCHEMBL4972827 | 0.69 | GPR119 (0.39) | HTR2AKCNH2GPR119ATRVCP | |
| SCHEMBL4050438 | 0.69 | GPR119 (0.43) | KCNH2RORCGPR119ATRJAK2 | |
| SCHEMBL3982003 | 0.69 | PAICS (0.48) | KCNH2GPR119JAK2 | |
| Hydrochloric Acid SCHEMBL4055905 | 0.69 | GPR119 (0.43) | KCNH2RORCGPR119ATRJAK2 | |
| SCHEMBL4457004 | 0.68 | HSP90AA1 (0.42) | KCNH2GPR119 | |
| SCHEMBL13690743 | 0.67 | VCP (0.48) | GPR119ATRVCPCKS1BSKP1 | |
| SCHEMBL4053994 | 0.67 | GPR119 (0.42) | RORCGPR119ATRCPT2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |