SCHEMBL438800

SCHEMBL438800

Fc1ccc(OBOc2ccc(F)cc2F)c(F)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
HSPB1 P04792 4/20 0.41
TRPA1 O75762 6/20 0.40
IDO1 P14902 2/20 0.38
AGXT P21549 2/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
CA3 P07451 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333943 0.86 CA3 (0.41) ALDH1A1HSPB1TRPA1IDO1AGXT
SCHEMBL28150210 0.82 POLB (0.35) ALDH1A1HSPB1TRPA1IDO1AGXT
SCHEMBL12157430 0.82 TRPA1 (0.39) ALDH1A1HSPB1TRPA1CES2CES1
SCHEMBL1702678 0.77 ALDH1A1 (0.33) ALDH1A1
SCHEMBL1174545 0.77 ACHE (0.41) ALDH1A1CA9
SCHEMBL1174046 0.77 PPARG (0.44) ALDH1A1
SCHEMBL3151958 0.77 MAPK1 (0.41) ALDH1A1
SCHEMBL593480 0.77 SLC6A4 (0.39) ALDH1A1
SCHEMBL2477993 0.77 CA3 (0.48) IDO1CA3CA6CA5ACA9
SCHEMBL337001 0.77 SLC6A4 (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106589321-B Preparation method and applications based on cationic conjugated polymer Yu the fluorescent optical sensor system of complex of iridium FRET effect 宁波大学 2019-11-12 CN claimed
CN-104530135-A Blue-phosphorescence pyrimidine iridium complex and preparation method thereof UNIV NINGBO 2015-04-22 CN claimed
CN-104402936-A Iridium complex and preparation method thereof UNIV NINGBO 2015-03-11 CN claimed
CN-104370973-A Iridium complex and preparation method thereof UNIV NINGBO 2015-02-25 CN claimed
WO-2026107178-A1 GLOBAL AFFINITY PROFILING OF MOLECULAR INTERACTIONS USING COMPETITIVE ENRICHMENT CORNELL UNIVERSITY (US) 2026-05-21 WO disclosed
WO-2026099455-A1 DIHYDROPYRROLOPYRIMIDINONE COMPOUNDS AS TREM2 MODULATORS MUNA THERAPEUTICS APS (DK) 2026-05-15 WO disclosed
US-20260097034-A1 METALLOENZYME INHIBITOR COMPOUNDS CORXEL PHARMACEUTICALS HONG KONG LTD (HK) 2026-04-09 US disclosed
EP-4146220-B1 HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE AMGEN INC (US) 2026-02-18 EP disclosed
US-12527776-B2 Treatment of ciliopathies using inhibitors of glucosylceramide synthase (GCS) GENZYME CORPORATION (US) 2026-01-20 US disclosed
US-20250362302-A1 INTRACELLULAR LIGATION OF PHOTOCATALYSTS FOR PHOTO-RESPONSIVE, PROBE-MEDIATED PROTEIN LABELING SEED THERAPEUTICS US INC (US) 2025-11-27 US disclosed
US-12458642-B2 Metalloenzyme inhibitor compounds CORXEL PHARMACEUTICALS HONG KONG LIMITED (HK) 2025-11-04 US disclosed
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-10-30 US disclosed
US-6232320-B1 THIENO(2,3-C)PYRIDINE AND 5H-THIENO(2,3-C)PYRAN DERIATIVES ABBOTT LABORATORIES 2001-05-15 US disclosed
WO-2001029012-A2 BENZODIAZEPINE DERIVATIVES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2001-04-26 WO disclosed
EP-1090009-A2 CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS ABBOTT LABORATORIES (US) 2001-04-11 EP disclosed
WO-2000075145-A1 CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS ABBOTT LABORATORIES (US) 2000-12-14 WO disclosed
WO-1999062908-A2 CELL ADHESION-INHIBITING ANTINFLAMMATORY COMPOUNDS ABBOTT LABORATORIES (US) 1999-12-09 WO disclosed
EP-0413785-B1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK PATENT GMBH (DE) 1995-12-20 EP disclosed
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527776-B2 Treatment of ciliopathies using inhibitors of glucosylceramide synthase (GCS) GBA1, GBA2, GALC ALDH1A1 1394/4885HSPB1 834/4885TRPA1 2635/4885
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SCNN1B, SCN1B, SCN2B ALDH1A1 1252/4885HSPB1 1468/4885TRPA1 72/4885
US-12458642-B2 Metalloenzyme inhibitor compounds CYP11B2, CYP11B1, HSD11B2 ALDH1A1 232/4885HSPB1 1945/4885TRPA1 2857/4885
US-20260097034-A1 METALLOENZYME INHIBITOR COMPOUNDS CPN1, TPP1, DPP4 ALDH1A1 189/4885HSPB1 1675/4885TRPA1 3611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.