Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439948 | 0.89 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EHSD17B10CSF1R | |
| SCHEMBL1644467 | 0.86 | THRB (0.46) | ALDH1A1HPGDKDM4EHSD17B10CSF1R | |
| SCHEMBL30592902 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10CSF1R | |
| SCHEMBL3887756 | 0.84 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10CSF1R | |
| Hydrochloric Acid SCHEMBL11870232 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EHSD17B10CSF1R | |
| SCHEMBL4466003 | 0.83 | SORT1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10CSF1R | |
| SCHEMBL437005 | 0.81 | THRB (0.60) | ALDH1A1KDM4EKMT2ATHRB | |
| SCHEMBL438745 | 0.81 | KEAP1 (0.49) | ALDH1A1KDM4ECSF1RMEN1KMT2A | |
| SCHEMBL27855175 | 0.79 | CSF1R (0.51) | CSF1RPARP1KMT2ATHRBMAP4K4 | |
| SCHEMBL5757387 | 0.78 | KDM4C (0.51) | ALDH1A1HPGDKDM4EHSD17B10PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |