Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438818 | 0.89 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EHSD17B10ALOX5AP | |
| SCHEMBL7688966 | 0.84 | DHODH (0.47) | ALDH1A1HPGDKDM4EHSD17B10ALOX5AP | |
| SCHEMBL7555337 | 0.83 | DHODH (0.46) | ALDH1A1HPGDKDM4EHSD17B10ALOX5AP | |
| SCHEMBL441445 | 0.81 | PDE5A (0.55) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL440033 | 0.81 | KEAP1 (0.49) | ALDH1A1DHODHHAVCR2MEN1KMT2A | |
| SCHEMBL16621492 | 0.79 | HAVCR2 (0.47) | ALDH1A1KDM4EHSD17B10HAVCR2CSNK1D | |
| SCHEMBL23935164 | 0.79 | BACE1 (0.45) | ALDH1A1HPGDKDM4EHSD17B10ALOX5AP | |
| SCHEMBL29742208 | 0.79 | BACE1 (0.45) | ALDH1A1HPGDKDM4EHSD17B10ALOX5AP | |
| SCHEMBL440411 | 0.78 | HAVCR2 (0.52) | ALDH1A1HPGDHSD17B10DHODHHAVCR2 | |
| SCHEMBL436603 | 0.78 | KDM4E (0.48) | ALDH1A1HPGDKDM4EHSD17B10DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |