Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | Q9HBH1 | 1/20 | 0.32 | |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4334971 | 0.78 | PADI4 (0.37) | F2DPP8DPP7PDFITGB3 | |
| SCHEMBL3072264 | 0.75 | NOS3 (0.33) | BLM | |
| SCHEMBL8067791 | 0.75 | KDM4E (0.46) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Trifluoroacetic Acid SCHEMBL6761033 | 0.72 | CA12 (0.38) | ||
| Trifluoroacetic Acid SCHEMBL6762932 | 0.72 | CA12 (0.40) | F2PDF | |
| Trifluoroacetic Acid SCHEMBL4324189 | 0.72 | CA12 (0.40) | F2PDF | |
| Trifluoroacetic Acid SCHEMBL4334998 | 0.72 | CA12 (0.40) | F2PDF | |
| Trifluoroacetic Acid SCHEMBL6542389 | 0.71 | LMNA (0.39) | THRBALOX15BLMF2ALDH1A1 | |
| SCHEMBL21051914 | 0.70 | TGFBR1 (0.42) | — | |
| SCHEMBL165977 | 0.70 | MME (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612075-B2 | Substituted oxoazaheterocyclyl compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2009-11-03 | — | — | US | disclosed |