Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440082 | 0.86 | LMNA (0.47) | ACHEBCHEGRIN1GRIN2APARP1 | |
| SCHEMBL12210442 | 0.81 | ACHE (0.49) | ACHEBCHEGRIN1GRIN2ACHEK1 | |
| SCHEMBL438932 | 0.79 | ACHE (0.46) | ACHEBCHEGRIN1GRIN2ATNF | |
| SCHEMBL438239 | 0.79 | ACHE (0.46) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL437293 | 0.79 | ACHE (0.43) | ACHEBCHEGRIN1GRIN2ACHEK1 | |
| SCHEMBL440277 | 0.78 | ACHE (0.50) | ACHEBCHEPLGPLAUHTR1A | |
| SCHEMBL441831 | 0.78 | ALDH1A1 (0.46) | ACHEBCHEGRIN1GRIN2ATNF | |
| SCHEMBL436602 | 0.75 | ACHE (0.44) | ACHEPIM1ALDH1A1CYP3A4 | |
| SCHEMBL438632 | 0.75 | PARP1 (0.45) | PARP1KDM4EALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL437696 | 0.73 | KDM4E (0.50) | ACHEBCHEGRIN1GRIN2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |