Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 9/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074851 | 0.85 | ACHE (0.45) | ACHEPTGESBACE1PDPK1JAK2 | |
| SCHEMBL20476253 | 0.85 | ACHE (0.45) | ACHEPTGESBACE1PDPK1JAK2 | |
| SCHEMBL438613 | 0.85 | BCHE (0.45) | ACHEBACE1PDPK1JAK2PABPC1 | |
| SCHEMBL23037563 | 0.81 | ACHE (0.43) | ACHEPTGESBACE1PDPK1JAK2 | |
| SCHEMBL439004 | 0.81 | ACHE (0.43) | ACHEBACE1 | |
| SCHEMBL438932 | 0.81 | ACHE (0.46) | ACHEPTGESBACE1PDPK1JAK2 | |
| SCHEMBL437293 | 0.81 | ACHE (0.43) | ACHE | |
| SCHEMBL31728137 | 0.78 | PTGES (0.41) | ACHEPTGESBACE1PDPK1JAK2 | |
| SCHEMBL437067 | 0.78 | MAOB (0.46) | BACE1 | |
| SCHEMBL437945 | 0.78 | ACHE (0.47) | ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |