Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4389892 | 0.81 | AKT1 (0.34) | HPGDALDH1A1MAPTMAPK1 | |
| SCHEMBL5410631 | 0.75 | SMN1; SMN2 (0.61) | SMN1; SMN2KDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL4387095 | 0.72 | L3MBTL1 (0.34) | HPGDALDH1A1MAPTTDP1 | |
| SCHEMBL29437683 | 0.71 | ALDH1A1 (0.42) | SMN1; SMN2KDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL28699051 | 0.71 | ALDH1A1 (0.42) | SMN1; SMN2KDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL20521131 | 0.71 | MAPT (0.38) | HPGDALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL1044902 | 0.70 | CES2 (0.52) | SMN1; SMN2KDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL30848560 | 0.68 | HDAC1 (0.63) | SMN1; SMN2KDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL11330833 | 0.66 | BCL2L1 (0.35) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9575208 | 0.66 | KDM4E (0.68) | SMN1; SMN2KDM4EHPGDALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917281-B2 | POLYMERIZATION CATALYSTS AND PROCESS FOR PRODUCING BIMODAL POLYMERS IN A SINGLE REACTOR | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2019-01-09 | — | — | EP | disclosed |
| EP-1917281-B1 | POLYMERIZATION CATALYSTS AND PROCESS FOR PRODUCING BIMODAL POLYMERS IN A SINGLE REACTOR | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-05-13 | — | — | EP | disclosed |
| EP-1917281-A1 | POLYMERIZATION CATALYSTS AND PROCESS FOR PRODUCING BIMODAL POLYMERS IN A SINGLE REACTOR | Chevron Phillips Chemical Company LP (US) | 2008-05-07 | — | — | EP | disclosed |
| US-7312283-B2 | Polymerization catalysts and process for producing bimodal polymers in a single reactor | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2007-12-25 | — | — | US | disclosed |
| WO-2007024773-A1 | POLYMERIZATION CATALYSTS AND PROCESS FOR PRODUCING BIMODAL POLYMERS IN A SINGLE REACTOR | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2007-03-01 | — | — | WO | disclosed |
| US-20070043176-A1 | Polymerization catalysts and process for producing bimodal polymers in a single reactor | CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. | 2007-02-22 | — | — | US | disclosed |