Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439646 | 0.77 | HAVCR2 (0.32) | TET2EPHB4BTKDYRK1A | |
| SCHEMBL435823 | 0.74 | PARP1 (0.41) | TET2 | |
| SCHEMBL437507 | 0.74 | MAP4K4 (0.35) | TET2EPHB4MAP4K4MINK1TNIK | |
| SCHEMBL436994 | 0.72 | HAVCR2 (0.48) | BTK | |
| SCHEMBL28902617 | 0.71 | BTK (0.51) | BTKMAP4K4DYRK1A | |
| SCHEMBL439672 | 0.69 | DYRK1A (0.35) | EPHB4MAP4K4DYRK1A | |
| SCHEMBL436403 | 0.69 | POLB (0.38) | DYRK1A | |
| SCHEMBL439299 | 0.67 | BCHE (0.34) | EPHB4 | |
| SCHEMBL439456 | 0.67 | CDK8 (0.33) | TET2MAP4K4MINK1TNIKDYRK1A | |
| SCHEMBL10008366 | 0.65 | NR4A2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |