Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435823 | 0.79 | PARP1 (0.41) | TET2ALOX5APFEN1 | |
| SCHEMBL442157 | 0.79 | HAVCR2 (0.36) | ALOX5APFEN1 | |
| SCHEMBL439003 | 0.74 | TET2 (0.34) | MAP4K4MINK1TNIKTET2EPHB4 | |
| SCHEMBL436943 | 0.73 | HAVCR2 (0.56) | MAP4K4ALOX5APFEN1 | |
| SCHEMBL439739 | 0.73 | CCR1 (0.39) | MAP4K4MINK1TNIK | |
| SCHEMBL18281191 | 0.72 | MEN1 (0.38) | MAP4K4MINK1TNIK | |
| SCHEMBL442133 | 0.72 | BACE1 (0.41) | — | |
| SCHEMBL437599 | 0.71 | CCR1 (0.42) | — | |
| SCHEMBL439423 | 0.71 | HAVCR2 (0.36) | — | |
| SCHEMBL439456 | 0.71 | CDK8 (0.33) | MAP4K4MINK1TNIKTET2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |