Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391087 | 0.81 | HTR2A (0.48) | HTR2AOPRM1DRD4MEN1CYP2C9 | |
| SCHEMBL3552547 | 0.77 | SLC6A2 (0.42) | OPRM1CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL16212879 | 0.76 | CYP2D6 (0.40) | HTR2AOPRM1MAOBMAOADRD4 | |
| Hydrochloric Acid SCHEMBL7844207 | 0.74 | OPRM1 (0.48) | HTR2AOPRM1MAOBMAOA | |
| SCHEMBL23126472 | 0.70 | LMNA (0.34) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL27498994 | 0.68 | MAOB (0.55) | OPRM1SLC6A2SLC6A3MAOBMAOA | |
| SCHEMBL18703580 | 0.68 | OPRM1 (0.43) | OPRM1CHRNB2SLC6A2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL18689560 | 0.67 | OPRM1 (0.42) | OPRM1CHRNB2SLC6A2CHRNB4CHRNA3 | |
| SCHEMBL24481549 | 0.66 | HTR2A (0.67) | HTR2AOPRM1SLC6A2DRD4MEN1 | |
| SCHEMBL11019671 | 0.65 | CHRNB2 (0.39) | OPRM1CHRNB2SLC6A2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | THE UNIVERSITY OF CHICAGO (US) | 2021-03-23 | — | — | US | disclosed |
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | THE UNIVERSITY OF CHICAGO (US) | 2021-03-23 | — | — | US | disclosed |
| US-20180361370-A1 | STABILIZATION OF ACTIVE METAL CATALYSTS AT METAL-ORGANIC FRAMEWORK NODES FOR HIGHLY EFFICIENT ORGANIC TRANSFORMATIONS | NATIONAL SCIENCE FOUNDATION | 2018-12-20 | — | — | US | disclosed |
| US-20120190854-A1 | Hydroamination of Alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190854-A1 | Hydroamination of Alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190854-A1 | Hydroamination of Alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-07-26 | — | — | US | disclosed |
| US-8188302-B2 | Hydroamination of alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188302-B2 | Hydroamination of alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188302-B2 | Hydroamination of alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-05-29 | — | — | US | disclosed |
| EP-2227479-B1 | CYCLOPENTADIENYLPHOSPHAZENE COMPLEXES (CpPN COMPLEXES) OF METALS OF THE THIRD AND FOURTH GROUP AND OF THE LANTHANOIDS | UNIV MARBURG PHILIPPS (DE) | 2012-05-02 | — | — | EP | disclosed |
| EP-2227477-B1 | ORTHO-METALATED, CHELATE-STABILIZED BENZYLAMINES OF THE RARE EARTH METALS (RE) | UNIV MARBURG PHILIPPS (DE) | 2011-09-28 | — | — | EP | disclosed |
| US-20110034713-A1 | Ortho-metalated, chelate-stabilized benzylamines of the rare-earth metals (RE) Ar3RE | PHILIPPS-UNIVERSITAT MARBURG (DE) | 2011-02-10 | — | — | US | disclosed |
| US-20110034715-A1 | Cyclopentadienylphosphazene complexes (CpPN Complexes) of metals of the third and fourth group and of the lanthanoids | PHILIPPS-UNIVERSITAT MARBURG (DE) | 2011-02-10 | — | — | US | disclosed |
| US-20090156824-A1 | Hydroamination of Alkenes | BOARD OF TRUSTEES OF UNIVERSITY OF ILLINOIS (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090156824-A1 | Hydroamination of Alkenes | BOARD OF TRUSTEES OF UNIVERSITY OF ILLINOIS (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090156824-A1 | Hydroamination of Alkenes | BOARD OF TRUSTEES OF UNIVERSITY OF ILLINOIS (US) | 2009-06-18 | — | — | US | disclosed |
| WO-2009068000-A2 | CYCLOPENTADIENYLPHOSPHAZENE COMPLEXES (CpPN COMPLEXES) OF METALS OF THE THIRD AND FOURTH GROUP AND OF THE LANTHANOIDS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2009-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156824-A1 | Hydroamination of Alkenes | HRH3, HRH4, H1-3 | HTR2A 2025/4885OPRM1 465/4885CHRNB2 1298/4885 |
| US-20110034715-A1 | Cyclopentadienylphosphazene complexes (CpPN Complexes) of metals of the third and fourth group and of the lanthanoids | CPNE4, CPN1, NCLN | HTR2A 3670/4885OPRM1 3533/4885CHRNB2 591/4885 |
| US-20110034713-A1 | Ortho-metalated, chelate-stabilized benzylamines of the rare-earth metals (RE) Ar3RE | AR, BAG3, MAPRE2 | HTR2A 1544/4885OPRM1 40/4885CHRNB2 2811/4885 |
| US-10953393-B2 | Stabilization of active metal catalysts at metal-organic framework nodes for highly efficient organic transformations | SBK1, SIK1, SIK2 | HTR2A 743/4885OPRM1 1545/4885CHRNB2 3598/4885 |
| US-20180361370-A1 | STABILIZATION OF ACTIVE METAL CATALYSTS AT METAL-ORGANIC FRAMEWORK NODES FOR HIGHLY EFFICIENT ORGANIC TRANSFORMATIONS | SBK1, SIK1, SIK2 | HTR2A 743/4885OPRM1 1545/4885CHRNB2 3598/4885 |
| US-20120190854-A1 | Hydroamination of Alkenes | HRH3, HRH4, H1-3 | HTR2A 2025/4885OPRM1 465/4885CHRNB2 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.