Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17666180 | 0.78 | SMN1; SMN2 (0.44) | OPRM1DRD4KCNH2LMNASMN1; SMN2 | |
| SCHEMBL4395771 | 0.78 | OPRM1 (0.43) | OPRM1DRD4KCNH2LMNASMN1; SMN2 | |
| SCHEMBL4395795 | 0.75 | MAPT (0.42) | OPRM1DRD4LMNAOPRD1OPRK1 | |
| SCHEMBL4401474 | 0.75 | MAPT (0.45) | OPRM1LMNAOPRD1OPRK1MAPT | |
| SCHEMBL26568813 | 0.73 | PDK2 (0.49) | OPRM1LMNAALDH1A1HTTOPRK1 | |
| SCHEMBL12367138 | 0.72 | OPRM1 (0.69) | OPRM1DRD4KCNH2LMNASMN1; SMN2 | |
| SCHEMBL11949296 | 0.71 | LMNA (0.44) | OPRM1LMNAALDH1A1MAPT | |
| SCHEMBL4396595 | 0.71 | CYP3A4 (0.42) | OPRM1ALDH1A1OPRD1OPRK1MAPT | |
| SCHEMBL4396042 | 0.71 | SIGMAR1 (0.41) | OPRM1DRD4ALDH1A1CHRM2MAPT | |
| SCHEMBL15037443 | 0.71 | SLC18A3 (0.44) | OPRM1DRD4KCNH2SMN1; SMN2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156824-A1 | Hydroamination of Alkenes | BOARD OF TRUSTEES OF UNIVERSITY OF ILLINOIS (US) | 2009-06-18 | — | — | US | claimed |
| US-12590054-B2 | Use of D9-methadone for postoperative pain relief | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2026-03-31 | — | — | US | disclosed |
| CN-107664693-B | Carrier for preventing flooding of detection reagent strips | 杭州博拓生物科技股份有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-107664702-B | Device for detecting analyte in sample | 杭州博拓生物科技股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| US-20240116851-A1 | USE OF D9-METHADONE FOR POSTOPERATIVE PAIN RELIEF | UNIV TEXAS (US) | 2024-04-11 | — | — | US | disclosed |
| WO-2016040822-A1 | READY-TO-CONSTITUTE ANALYTICAL PLATFORMS FOR CHEMICAL ANALYSES AND QUANTIFICATION | PINPOINT TESTING, LLC (US) | 2016-03-17 | — | — | WO | disclosed |
| US-20120190854-A1 | Hydroamination of Alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190854-A1 | Hydroamination of Alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190854-A1 | Hydroamination of Alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-07-26 | — | — | US | disclosed |
| US-8188302-B2 | Hydroamination of alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188302-B2 | Hydroamination of alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-05-29 | — | — | US | disclosed |
| US-8188302-B2 | Hydroamination of alkenes | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090156824-A1 | Hydroamination of Alkenes | BOARD OF TRUSTEES OF UNIVERSITY OF ILLINOIS (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090156824-A1 | Hydroamination of Alkenes | BOARD OF TRUSTEES OF UNIVERSITY OF ILLINOIS (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090156824-A1 | Hydroamination of Alkenes | BOARD OF TRUSTEES OF UNIVERSITY OF ILLINOIS (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116851-A1 | USE OF D9-METHADONE FOR POSTOPERATIVE PAIN RELIEF | OPRM1, OPRD1, OPRK1 | OPRM1 1/4885DRD4 46/4885KCNH2 587/4885 |
| US-20090156824-A1 | Hydroamination of Alkenes | HRH3, HRH4, H1-3 | OPRM1 465/4885DRD4 272/4885KCNH2 1221/4885 |
| US-12590054-B2 | Use of D9-methadone for postoperative pain relief | OPRM1, OPRD1, OPRK1 | OPRM1 1/4885DRD4 97/4885KCNH2 447/4885 |
| US-20120190854-A1 | Hydroamination of Alkenes | HRH3, HRH4, H1-3 | OPRM1 465/4885DRD4 272/4885KCNH2 1221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.