Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLKL | Q8NB16 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073877 | 0.93 | MLKL (0.44) | MLKLKMT2AMEN1GAALMNA | |
| SCHEMBL13814969 | 0.93 | MLKL (0.44) | MLKLKMT2AMEN1GAALMNA | |
| SCHEMBL8986307 | 0.87 | MLKL (0.40) | MLKLKMT2AMEN1LMNATSHR | |
| SCHEMBL14282583 | 0.84 | MLKL (0.40) | MLKLKMT2ALMNATSHRHSD17B10 | |
| SCHEMBL4376113 | 0.78 | PTPN1 (0.33) | MLKL | |
| SCHEMBL4388274 | 0.78 | MLKL (0.31) | MLKL | |
| SCHEMBL10297403 | 0.76 | MLKL (0.35) | MLKL | |
| SCHEMBL10073878 | 0.75 | ACP3 (0.46) | KMT2AGAATSHRCYP2D6CYP2C19 | |
| SCHEMBL96180 | 0.73 | ACHE (0.50) | MLKLKMT2AACHECHRNA7LMNA | |
| Hydrochloric Acid SCHEMBL29699724 | 0.71 | ACHE (0.47) | MLKLKMT2AACHECHRNA7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445695-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |
| US-8445695-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120322999-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | LINDSEY JONATHAN S (US) | 2012-12-20 | — | — | US | disclosed |
| US-20120322999-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | LINDSEY JONATHAN S (US) | 2012-12-20 | — | — | US | disclosed |
| US-8278439-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-10-02 | — | — | US | disclosed |
| US-8278439-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120065391-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | LINDSEY JONATHAN S (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065391-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | LINDSEY JONATHAN S (US) | 2012-03-15 | — | — | US | disclosed |
| US-8080653-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-12-20 | — | — | US | disclosed |
| US-8080653-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-12-20 | — | — | US | disclosed |
| US-20090234136-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | LINDSEY JONATHAN S | 2009-09-17 | — | — | US | disclosed |
| US-20090234136-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | LINDSEY JONATHAN S | 2009-09-17 | — | — | US | disclosed |
| US-7553977-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-06-30 | — | — | US | disclosed |
| US-7553977-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080269501-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269501-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-10-30 | — | — | US | disclosed |
| US-7314941-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-01-01 | — | — | US | disclosed |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-05-17 | — | — | US | disclosed |
| US-20070055060-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | LINDSEY JONATHAN S | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269501-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | PPOX, DAO, DDO | MLKL 4050/4885KMT2A 3335/4885MEN1 1918/4885 |
| US-20120322999-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | PPOX, DAO, DDO | MLKL 4050/4885KMT2A 3335/4885MEN1 1918/4885 |
| US-20090234136-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | PPOX, DAO, DDO | MLKL 4050/4885KMT2A 3335/4885MEN1 1918/4885 |
| US-20070055060-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | PPOX, DAO, DDO | MLKL 4050/4885KMT2A 3335/4885MEN1 1918/4885 |
| US-20070108438-A1 | Multypodal tethers for high-density attachment of redox-active moieties to substrates | DNMT1, TET1, SOD1 | MLKL 2293/4885KMT2A 441/4885MEN1 2704/4885 |
| US-20120065391-A1 | SYNTHESIS OF PHOSPHONO-SUBSTITUTED PORPHYRIN COMPOUNDS FOR ATTACHMENT TO METAL OXIDE SURFACES | PPOX, DAO, DDO | MLKL 4050/4885KMT2A 3335/4885MEN1 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.