Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLKL | Q8NB16 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073877 | 1.00 | MLKL (0.44) | MLKLLMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8986307 | 0.94 | MLKL (0.40) | MLKLLMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL439140 | 0.93 | MLKL (0.41) | MLKLLMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL14282583 | 0.90 | MLKL (0.40) | MLKLLMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10073878 | 0.83 | ACP3 (0.46) | CYP2D6CYP2C19KMT2ATSHRHSD17B2 | |
| SCHEMBL477385 | 0.78 | LMNA (0.50) | MLKLLMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL477533 | 0.78 | LMNA (0.50) | MLKLLMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL477590 | 0.78 | LMNA (0.50) | MLKLLMNACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL60997 | 0.73 | LMNA (0.53) | LMNAKMT2ATSHRMEN1CNR1 | |
| SCHEMBL3657920 | 0.73 | LMNA (0.53) | LMNAKMT2ATSHRMEN1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553977-B2 | Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080269501-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269501-A1 | Synthesis of Phosphono-Substituted Porphyrin Compounds for Attachment to Metal Oxide Surfaces | PPOX, DAO, DDO | MLKL 4050/4885LMNA 4355/4885CYP3A4 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.