Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439618 | 0.75 | ALDH1A1 (0.42) | KDM4EPOLBALDH1A1GAAHSD17B10 | |
| SCHEMBL439327 | 0.73 | SMN1; SMN2 (0.38) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL441514 | 0.69 | SLC2A1 (0.43) | KDM4ESLC2A1MEN1KMT2A | |
| SCHEMBL438559 | 0.69 | BRD4 (0.36) | NPSR1KDM4EPOLBALDH1A1HPGD | |
| SCHEMBL6402986 | 0.66 | MAPT (0.59) | NPSR1KDM4EPOLBALDH1A1HPGD | |
| SCHEMBL11474236 | 0.62 | NPSR1 (0.44) | NPSR1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8718496 | 0.61 | GABRA1 (0.48) | KDM4EPOLBALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9910161 | 0.61 | PPARD (0.35) | KDM4EALDH1A1GAA | |
| SCHEMBL5816059 | 0.61 | KDM4E (0.60) | NPSR1KDM4EPOLBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL29057693 | 0.60 | GABRA1 (0.34) | KDM4EPOLBALDH1A1GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513277-B2 | Pyrrolo[3,2-C] pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2013-08-20 | — | — | US | disclosed |
| US-8148529-B2 | Pyrrolo[3,2-C] pyridine derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2012-04-03 | — | — | US | disclosed |
| US-20120065224-A1 | PYRROLO[3,2-C) PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2012-03-15 | — | — | US | disclosed |
| EP-1784402-B1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-08-03 | — | — | EP | disclosed |
| US-20090005409-A1 | Pyrrolo[3,2-C] Pyrdine Derivatives and Processes for the Preparation Thereof | YUHAN CORPORATION (KR) | 2009-01-01 | — | — | US | disclosed |
| EP-1784402-A1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006025714-A1 | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005409-A1 | Pyrrolo[3,2-C] Pyrdine Derivatives and Processes for the Preparation Thereof | ATP6AP1, PPOX, PGA5 | NPSR1 1956/4885KDM4E 1871/4885POLB 3000/4885 |
| US-20120065224-A1 | PYRROLO[3,2-C) PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | PGA5, ATP6AP1, HPD | NPSR1 1854/4885KDM4E 1016/4885POLB 3190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.