SCHEMBL439211

SCHEMBL439211

CC([C](c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.46
LMNA P02545 3/20 0.46
MAPT P10636 2/20 0.46
PTGS1 P23219 2/20 0.46
CXCR1 P25024 2/20 0.46
CXCR2 P25025 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 2/20 0.46
THPO P40225 2/20 0.46
KDM4E B2RXH2 2/20 0.46
HIF1A Q16665 2/20 0.46
ALDH1A1 P00352 2/20 0.46
RECQL P46063 1/20 0.46
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.46
PMP22 Q01453 1/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
CXCL8 P10145 1/20 0.46
ADRA2C P18825 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2037726 0.80 PTGS2 (0.46) PTGS2LMNAMAPTPTGS1CXCR1
SCHEMBL1518530 0.78 PTGS2 (0.44) PTGS2LMNAMAPTPTGS1CXCR1
SCHEMBL1383906 0.77 LMNA (0.60) LMNACYP3A4HSD17B10THPOKDM4E
SCHEMBL7617096 0.76 PTGS2 (0.47) PTGS2LMNAMAPTPTGS1CXCR1
SCHEMBL702447 0.76 TDP1 (0.61) PTGS2LMNAMAPTPTGS1CXCR1
SCHEMBL9717408 0.76 SMN1; SMN2 (0.47) PTGS2LMNAMAPTPTGS1CXCR1
SCHEMBL13706027 0.76 PTGS2 (0.43) PTGS2LMNAMAPTPTGS1CXCR1
SCHEMBL9747262 0.76 PTGS2 (0.43) PTGS2LMNAMAPTPTGS1CXCR1
SCHEMBL5088282 0.76 PTGS2 (0.43) PTGS2LMNAMAPTPTGS1CXCR1
SCHEMBL10894082 0.76 TDP1 (0.61) PTGS2LMNAMAPTPTGS1CXCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599753-A Polishing composition and method with high selectivity for silicon nitride and polysilicon versus silicon oxide CMC材料股份有限公司 2022-06-07 CN claimed
US-8779128-B2 Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups SAREPTA THERAPEUTICS, INC. (US) 2014-07-15 US claimed
EP-2576574-A2 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS Sarepta Therapeutics, Inc. (US) 2013-04-10 EP claimed
US-20120065169-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2012-03-15 US claimed
WO-2011150408-A2 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS AVI BIOPHARMA, INC. (US) 2011-12-01 WO claimed
JP-3553083-B2 2004-08-11 JP claimed
EP-0852494-A2 PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-07-15 EP claimed
WO-1997009973-A2 PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-03-20 WO claimed
US-20240239745-A1 METHOD FOR SYNTHESIZING BILIRUBIN Bilix Co., Ltd. (KR) 2024-07-18 US disclosed
EP-4375280-A1 METHOD FOR SYNTHESIZING BILIRUBIN Bilix Co., Ltd. (KR) 2024-05-29 EP disclosed
CN-118103209-A Composition for forming release layer, laminate, and method for producing laminate 日产化学株式会社 2024-05-28 CN disclosed
EP-4371984-A1 METHOD FOR SYNTHESIZING BILIRUBIN Bilix Co., Ltd. (KR) 2024-05-22 EP disclosed
EP-4371985-A1 METHOD FOR SYNTHESIZING BILIRUBIN Bilix Co., Ltd. (KR) 2024-05-22 EP disclosed
CN-113166554-B xanthene compounds 株式会社艾迪科 2023-12-12 CN disclosed
US-6399727-B1 COMPLEX BASF AKTIENGESELLSCHAFT (DE) 2002-06-04 US disclosed
US-6372779-B1 ANTHRACENE DERIVATIVES WITH CARBAMOYL GROUPS, AMIDO GROUPS, UREA GROUPS AND SULFONAMIDE GROUPS ORTHO PHARMACEUTICAL CORPORATION 2002-04-16 US disclosed
EP-0966430-A1 ANTI-INFLAMMATORY COMPOUNDS Ortho-Mcneil Pharmaceutical Corp. (US) 1999-12-29 EP disclosed
WO-1999033786-A1 ANTI-INFLAMMATORY COMPOUNDS ORTHO-MCNEIL PHARMACEUTICAL CORPORATION (US) 1999-07-08 WO disclosed
EP-0686063-A1 A METHOD FOR SEPARATING CATALYST FROM A HYDROFORMYLATION REACTION PRODUCT USING ALKYLATED LIGANDS EXXON CHEMICAL PATENTS INC. (US) 1995-12-13 EP disclosed
WO-1994019104-A1 A METHOD FOR SEPARATING CATALYST FROM A HYDROFORMYLATION REACTION PRODUCT USING ALKYLATED LIGANDS EXXON CHEMICAL PATENTS INC. (US) 1994-09-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065169-A1 OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS NSUN2, UPF1, RTCB PTGS2 3715/4885LMNA 2297/4885MAPT 2188/4885
US-20240239745-A1 METHOD FOR SYNTHESIZING BILIRUBIN CYP7A1, UGT1A3, UGT1A1 PTGS2 422/4885LMNA 1887/4885MAPT 2689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.