Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | NCF1 | P14598 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27890180 | 0.88 | ALDH1A1 (0.62) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL27906713 | 0.84 | ALDH1A1 (0.65) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL437286 | 0.82 | HSD17B10 (0.71) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL3649291 | 0.81 | L3MBTL1 (0.50) | ALDH1A1CASP1CASP7HSD17B10BCHE | |
| SCHEMBL3647767 | 0.81 | MAPT (0.61) | ALDH1A1CASP1CASP7HSD17B10BCHE | |
| SCHEMBL3471999 | 0.79 | ALDH1A1 (1.00) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL439655 | 0.78 | ALDH1A1 (0.80) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL439264 | 0.77 | HSD17B10 (0.64) | ALDH1A1CASP1CASP7HSD17B10NCF1 | |
| SCHEMBL4077115 | 0.76 | TERT (0.69) | MEN1KMT2AMMP1MMP9ALOX15 | |
| SCHEMBL10251583 | 0.76 | NCF1 (0.53) | ALDH1A1CASP1CASP7HSD17B10NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117079-A1 | ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |