Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.90 |
| ▸ | HTR1A | P08908 | 3/20 | 0.73 |
| ▸ | BCHE | P06276 | 2/20 | 0.73 |
| ▸ | ACHE | P22303 | 2/20 | 0.73 |
| ▸ | HTR1B | P28222 | 2/20 | 0.73 |
| ▸ | HTR2A | P28223 | 2/20 | 0.73 |
| ▸ | HTR2C | P28335 | 2/20 | 0.73 |
| ▸ | HTR2B | P41595 | 2/20 | 0.73 |
| ▸ | SPR | P35270 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468610 | 0.94 | MTNR1A (0.97) | MTNR1AHTR1ABCHEACHEHTR1B | |
| SCHEMBL19411584 | 0.92 | MTNR1A (0.77) | MTNR1AHTR1ABCHEACHEHTR1B | |
| SCHEMBL13745656 | 0.89 | MTNR1A (0.77) | MTNR1AHTR1ABCHEACHEHTR1B | |
| SCHEMBL9358598 | 0.89 | MTNR1A (0.72) | MTNR1AHTR1ABCHEACHEHTR1B | |
| SCHEMBL13203825 | 0.86 | MTNR1A (0.68) | MTNR1AHTR1ABCHEACHEHTR1B | |
| SCHEMBL10113302 | 0.86 | MTNR1A (0.68) | MTNR1AHTR1ABCHEACHEHTR1B | |
| SCHEMBL10114080 | 0.85 | MTNR1A (0.67) | MTNR1AHTR1ABCHEACHEHTR1B | |
| SCHEMBL27572262 | 0.84 | MTNR1A (0.72) | MTNR1AHTR1ABCHEACHEHTR1B | |
| SCHEMBL9123061 | 0.83 | SPR (1.00) | MTNR1AHTR2CSPRKMT2AMEN1 | |
| SCHEMBL18381269 | 0.83 | MTNR1A (0.71) | MTNR1AHTR1ABCHEACHEHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005430-A1 | Receptor Blocker and Vasodilator Comprising Indole Derivative as Active Ingredient | NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005430-A1 | Receptor Blocker and Vasodilator Comprising Indole Derivative as Active Ingredient | ADRB2, ADRB1, ADRA2B | MTNR1A 261/4885HTR1A 34/4885BCHE 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.