Sugi Predict

Sugi Predict / Compounds / SCHEMBL439509

SCHEMBL439509

SCHEMBL439509

CC(C)CCCN1CCCC1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 2/20 0.52
▸ MAPT P10636 1/20 0.46
▸ GBA1 P04062 2/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ CARM1 Q86X55 1/20 0.41
▸ PRMT6 Q96LA8 1/20 0.41
▸ PRMT8 Q9NR22 1/20 0.41
▸ CACNA2D1 P54289 1/20 0.41
▸ LSS P48449 1/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ FPR3 P25089 1/20 0.38
▸ FPR2 P25090 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172955 0.98 HRH3 (0.56) HRH3MAPTGBA1MEN1KMT2A
SCHEMBL439729 0.98 HRH3 (0.56) HRH3MAPTGBA1MEN1KMT2A
SCHEMBL441042 0.95 HRH3 (0.46) HRH3MAPTGBA1MEN1KMT2A
SCHEMBL439740 0.93 HRH3 (0.56) HRH3MAPTMEN1KMT2ACARM1
SCHEMBL441058 0.91 HRH3 (0.61) HRH3MAPTMEN1KMT2ALSS
SCHEMBL21016238 0.91 HRH3 (0.61) HRH3MAPTMEN1KMT2ACARM1
SCHEMBL38662815 0.91 HRH3 (0.61) HRH3MAPTMEN1KMT2ACARM1
SCHEMBL20783151 0.89 HRH3 (0.43) HRH3MAPTGBA1MEN1KMT2A
Bromide SCHEMBL15941761 0.89 HRH3 (0.58) HRH3MAPTMEN1KMT2ACARM1
SCHEMBL7866253 0.89 HRH3 (0.65) HRH3MAPTLSSCYP1A2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12202848-B2 Phosphoramidite activator FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2025-01-21 — — US disclosed
US-20240166674-A1 PHOSPHORAMIDITE ACTIVATOR FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2024-05-23 — — US disclosed
WO-2024098053-A1 POLYMER-NUCLEIC ACID NANOPARTICLES FOR GENE EDITING THE JOHNS HOPKINS UNIVERSITY (US) 2024-05-10 — — WO disclosed
CN-114555617-B Phosphoramidite activators 富士胶片和光纯药株式会社 2024-03-08 — — CN disclosed
EP-4047004-B1 PHOSPHORAMIDITE ACTIVATOR FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2024-03-06 — — EP disclosed
WO-2024019936-A1 NANOMATERIALS COMPRISING TRIOLS BEAM THERAPEUTICS INC. (US) 2024-01-25 — — WO disclosed
EP-3833662-B1 INHIBITORS OF KEAP1-NRF2 PROTEIN-PROTEIN INTERACTION JANSSEN PHARMACEUTICA NV (BE) 2024-01-17 — — EP disclosed
US-20230399303-A1 Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same UNIV YALE (US) 2023-12-14 — — US disclosed
US-20230399303-A1 Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same UNIV YALE (US) 2023-12-14 — — US disclosed
US-11697804-B2 Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy THE JOHNS HOPKINS UNIVERSITY (US) 2023-07-11 — — US disclosed
US-20080027070-A1 2-AMINO--5-SUBSTITUTED PYRIMIDINE INHIBITORS TARGEGEN, INC. (US) 2008-01-31 — — US disclosed
WO-2007142986-A2 AMINOTHIAZOLE DERIVATIVES AND THEIR USES AS ANTIBACTERIAL AGENTS NOVARTIS AG (CH) 2007-12-13 — — WO disclosed
US-7291612-B2 Immunomodulatory compounds ACTIVE BIOTECH A.B. (SE) 2007-11-06 — — US disclosed
US-7276505-B2 Immunomodulating heterocyclic compounds MEDIGENE LIMITED (GB) 2007-10-02 — — US disclosed
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-09-06 — — US disclosed
US-7226950-B2 Sodium channel modulators THERAVANCE, INC. (US) 2007-06-05 — — US disclosed
WO-2007038829-A1 METHOD OF DRUG DESIGN ALCHEMIA LTD (AU) 2007-04-12 — — WO disclosed
US-7179815-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2007-02-20 — — US disclosed
US-20070021428-A1 Immunomodulating heterocyclic compounds AVIDEX LIMITED (GB) 2007-01-25 — — US disclosed
EP-1200073-B1 SELECTIVE iGluR 5? RECEPTOR ANTAGONISTS FOR THE TREATMENT OF MIGRAINE LILLY CO ELI (US) 2007-01-10 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166674-A1 PHOSPHORAMIDITE ACTIVATOR ITPA, INPP5D, INPP5B HRH3 2265/4885MAPT 2951/4885GBA1 745/4885
US-12202848-B2 Phosphoramidite activator ITPA, INPP5D, INPP5B HRH3 2265/4885MAPT 2951/4885GBA1 745/4885
US-11697804-B2 Transcriptionally targeted and CpG-free plasmid for theranostic gene therapy POLRMT, HDGF, PCNP HRH3 4611/4885MAPT 893/4885GBA1 4449/4885
US-20070021428-A1 Immunomodulating heterocyclic compounds CD40, CD40LG, NGFR HRH3 34/4885MAPT 4777/4885GBA1 4246/4885
US-20070208049-A1 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto GNRHR, GHRHR, LHCGR HRH3 229/4885MAPT 4761/4885GBA1 704/4885
US-20080027070-A1 2-AMINO--5-SUBSTITUTED PYRIMIDINE INHIBITORS KDR, FLT4, FLT1 HRH3 2012/4885MAPT 3941/4885GBA1 4800/4885
US-20230399303-A1 Macrophage Migration Inhibitory Factor Inhibitors, and Methods of Making and Using Same MIF, MMP12, METAP1 HRH3 3657/4885MAPT 371/4885GBA1 3013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.