Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403746 | 0.89 | CHRM2 (0.36) | SRD5A2MEN1KMT2ATMEM97FAAH | |
| SCHEMBL4404430 | 0.88 | HTR4 (0.37) | — | |
| SCHEMBL4409097 | 0.88 | CCR8 (0.44) | MEN1KMT2AALDH1A1FAAHCCR8 | |
| SCHEMBL4400739 | 0.87 | GUCY1B2 (0.37) | — | |
| SCHEMBL4403443 | 0.87 | MEN1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4401901 | 0.87 | HTR4 (0.46) | KMT2AALDH1A1SIGMAR1CCR8SMN1; SMN2 | |
| SCHEMBL4551166 | 0.86 | LMNA (0.42) | ALDH1A1CCR8 | |
| SCHEMBL4405631 | 0.86 | SSTR4 (0.40) | — | |
| SCHEMBL4402091 | 0.86 | LMNA (0.42) | ALDH1A1CCR8 | |
| SCHEMBL913937 | 0.86 | SRD5A2 (0.56) | SRD5A2MEN1KMT2ASGMS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |