Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL914614 | 0.87 | KDM4E (0.41) | MEN1KMT2AMCHR1KCNH2HTR7 | |
| SCHEMBL4396602 | 0.87 | SRD5A2 (0.47) | MEN1KMT2AALDH1A1 | |
| SCHEMBL4403746 | 0.86 | CHRM2 (0.36) | MEN1KMT2AMCHR1EPHX2KCNH2 | |
| SCHEMBL4404430 | 0.85 | HTR4 (0.37) | EPHX2HTR7HTR4HTR1A | |
| SCHEMBL4400739 | 0.84 | GUCY1B2 (0.37) | EPHX2HTR7HTR4HTR1A | |
| SCHEMBL4401901 | 0.84 | HTR4 (0.46) | KMT2AHTR4ALDH1A1HSD17B10 | |
| SCHEMBL4551166 | 0.83 | LMNA (0.42) | HTR7HTR4HTR1AALDH1A1 | |
| SCHEMBL4405631 | 0.83 | SSTR4 (0.40) | HTR7HTR4HTR1A | |
| SCHEMBL4402091 | 0.83 | LMNA (0.42) | HTR7HTR4HTR1AALDH1A1 | |
| SCHEMBL4406823 | 0.83 | HTR4 (0.38) | KMT2AMCHR1HTR4HTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |