Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409082 | 0.94 | SRD5A2 (0.36) | CHRM2CHRM1CHRM3SRD5A2MEN1 | |
| SCHEMBL4396602 | 0.89 | SRD5A2 (0.47) | SRD5A2MEN1KMT2ATMEM97FAAH | |
| SCHEMBL4406699 | 0.89 | KMT2A (0.34) | CHRM2CHRM1CHRM3SRD5A2MEN1 | |
| SCHEMBL4396316 | 0.89 | KMT2A (0.34) | CHRM2CHRM1CHRM3SRD5A2MEN1 | |
| SCHEMBL4405956 | 0.89 | FAAH (0.34) | CHRM2CHRM1CHRM3SRD5A2MEN1 | |
| SCHEMBL914012 | 0.87 | SRD5A2 (0.43) | CHRM2CHRM1CHRM3SRD5A2MEN1 | |
| SCHEMBL4411388 | 0.87 | CHRM2 (0.34) | CHRM2CHRM1CHRM3SRD5A2MEN1 | |
| SCHEMBL4403443 | 0.86 | MEN1 (0.35) | MEN1KMT2AEPHX2MCHR1KCNH2 | |
| SCHEMBL4404430 | 0.84 | HTR4 (0.37) | EPHX2HRH3HTR4HTR2A | |
| SCHEMBL4411341 | 0.84 | HTR1A (0.34) | SRD5A2MEN1KMT2AMCHR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |