Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.35 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.35 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.35 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4400739 | 0.97 | GUCY1B2 (0.37) | HTR4DRD2SLC6A4PARP1EPHX1 | |
| SCHEMBL4400766 | 0.93 | TERT (0.37) | DRD2SLC6A4PARP1PARP2HTR1A | |
| SCHEMBL4412712 | 0.91 | LMNA (0.36) | DRD2SLC6A4PARP1EPHX1HTR1A | |
| SCHEMBL4405338 | 0.91 | TERT (0.36) | DRD2SLC6A4PARP1HTR1ALMNA | |
| SCHEMBL4396907 | 0.89 | GUCY1B2 (0.34) | DRD2SLC6A4PARP1HTR1AGUCY1B2 | |
| SCHEMBL4401901 | 0.88 | HTR4 (0.46) | HTR4DRD2 | |
| SCHEMBL4405631 | 0.88 | SSTR4 (0.40) | HTR4HTR1ALMNAHTR7 | |
| SCHEMBL4551166 | 0.88 | LMNA (0.42) | HTR4PARP1HTR1ALMNAHTR7 | |
| SCHEMBL4402091 | 0.88 | LMNA (0.42) | HTR4PARP1HTR1ALMNAHTR7 | |
| SCHEMBL4396602 | 0.88 | SRD5A2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |