Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438887 | 0.86 | MCHR1 (0.44) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL438834 | 0.86 | NOS2 (0.50) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL441787 | 0.82 | MCHR1 (0.37) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL439825 | 0.80 | NR4A2 (0.60) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL438225 | 0.77 | MCHR1 (0.42) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL439885 | 0.76 | NOS3 (0.41) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL437444 | 0.75 | MCHR1 (0.60) | MCHR1ASIC3 | |
| SCHEMBL441901 | 0.75 | MCHR1 (0.43) | MCHR1NOS3NOS1NOS2ASIC3 | |
| SCHEMBL437497 | 0.75 | NR4A2 (0.62) | BCHEACHEGRIN1GRIN2AALDH1A1 | |
| SCHEMBL438576 | 0.74 | MCHR1 (0.49) | MCHR1NOS3NOS1NOS2ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |