Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439708 | 0.82 | MCHR1 (0.43) | MCHR1ASIC3NOS3NOS1NOS2 | |
| SCHEMBL438887 | 0.81 | MCHR1 (0.44) | MCHR1ASIC3NOS3NOS1NOS2 | |
| SCHEMBL438754 | 0.79 | HSP90AB1 (0.52) | MCHR1HSP90AB1 | |
| SCHEMBL439805 | 0.78 | NR4A2 (0.47) | MAPTHSP90AB1HSP90AA1CRHR1 | |
| SCHEMBL441438 | 0.77 | MAPT (0.43) | MCHR1NOS3NOS1NOS2MAPT | |
| SCHEMBL438834 | 0.72 | NOS2 (0.50) | MCHR1ASIC3NOS3NOS1NOS2 | |
| SCHEMBL437444 | 0.71 | MCHR1 (0.60) | MCHR1ASIC3 | |
| SCHEMBL439825 | 0.70 | NR4A2 (0.60) | MCHR1ASIC3NOS3NOS1NOS2 | |
| SCHEMBL438225 | 0.70 | MCHR1 (0.42) | MCHR1ASIC3NOS3NOS1NOS2 | |
| SCHEMBL438849 | 0.69 | NOS3 (0.41) | MCHR1ASIC3NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |